臨床泌尿器科74巻8号

2020年07月発行

特集 これが最新版！　過活動膀胱のトリセツ〈特別付録Web動画〉

〈過活動膀胱に対する新しい治療と未来展望〉

基礎研究からみた新しい治療の可能性

著者： 相澤直樹¹

所属機関： ¹獨協医科大学医学部薬理学講座

ページ範囲：P.608 - P.612

文献概要

▶ポイント

・病態時におけるnon-cholinergic収縮成分の増強と，それを治療標的とした創薬探索が模索されている．

・膀胱知覚求心路への作用は，尿意切迫感の病態解明および創薬探索に結びつく可能性がある．

・過活動膀胱（OAB）においても，ドラッグデリバリーシステム（DDS）を用いた効率的な薬物投与が，安全で副作用の少ない治療となりうる可能性がある．

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