臨床外科60巻6号

2005年06月発行

特集 化学放射線療法―現状とイメージングによる効果判定

局所進行膵癌に対する術前放射線・化学療法

著者： 石川治¹ 大東弘明¹ 江口英利¹ 山田晃正¹ 佐々木洋¹ 今岡真義¹ 西山謹司²

所属機関： ¹大阪府立成人病センター外科 ²大阪府立成人病センター放射線治療科

ページ範囲：P.759 - P.763

文献概要

要旨：過去10余年間に欧米を中心として局所進行膵癌を術前放射線・化学療法によって治療し，その後に手術を行うneoadjuvant therapyが徐々に普及してきた．同治療の完遂率や手術の安全性についてはほぼ確立された感があり，組織学的根治度や局所再発制御効果に優れているという報告が多い．無作為比較試験がないので遠隔成績の向上にどのくらい寄与できるかは未だ明らかではないが，肝転移再発対策などと併用すれば今後大いに期待できる治療戦略である．

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