1)Herder GJ, Verboom P, Smit EF, et al:Practice, efficacy and cost of staging suspected non-small cell lung cancer:a retrospective study in two Dutch hospitals. Thorax 57:11-14, 2002
2)Van Tinteren H, Hoekstra OS, Smit EF, et al:Effectiveness of positron emission tomography in the preoperative assessment of patients with suspected non-small-cell lung cancer:the PLUS multicentre randomised trial. Lancet 359:1388-1393, 2002
3)Goya T, Asamura H, Yoshimura H, et al:Prognosis of 6644 resected non-small cell lung cancers in Japan:a Japanese lung cancer registry study. Lung Cancer 50:227-234, 2005
4)Detterbeck FC, DeCamp MM, Kohman LJ, et al:Invasive staging:the guidelines. Chest 123:167-175, 2003
5)Felip E, Stahel RA, Pavlidis N, et al:ESMO minimum clinical recommendations for diagnosis, treatment and follow-up of non-small-cell lung cancer(NSCLC). Ann Oncol 16(Suppl 1):i 28-29, 2005
6)National Comprehensive Cancer Network. Clinical practice guidelines in oncology. Non-small cell lung cancer. available at:http://www.nccn.org/professionals/physician_gls/PDF/nscl.pdf. v.2.2006. accessed:25 August 2006
7)Silvestri GA, Tanoue LT, Margolis ML, et al:The noninvasive staging of non-small cell lung cancer:the guidelines. Chest 123:147-156, 2003
8)Reed CE, Harpole DH, Posther KE, et al:Results of the American College of Surgeons Oncology Group Z0050 Trial:the utility of positron emission tomography in staging potentially operable non-small cell lung cancer. J Thorac Cardiovasc Surg 126:1943-1951, 2003
9)Douillard J, Rosell R, Delena M, et al:Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage ⅠB-ⅢA non-small-cell lung cancer(Adjuvant Navelbine International Trialist Association[ANITA]):a randomised controlled trial. Lancet Oncol 7:719-727, 2006
10)Betticher DC, Hsu Schmitz SF, Totsch M, et al:Mediastinal lymph node clearance after docetaxel-cisplatin neoadjuvant chemotherapy is prognostic of survival in patients with stage ⅢA pN2 non-small-cell lung cancer:a multicenter phase Ⅱ trial. J Clin Oncol 21:1752-1759, 2003
11)Betticher DC, Hsu Schmitz SF, Totsch M, et al:Prognostic factors affecting long-term outcomes in patients with resected stage ⅢA pN2 non-small-cell lung cancer:5-year follow-up of a phase Ⅱ study. Br J Cancer 94:1099-1106, 2006
12)Radiation Therapy Oncology Group. Cisplatin and docetaxel with or without radiation therapy in treating patients who are undergoing surgery for newly diagnosed stage Ⅲ non-small cell lung cancer. 2006. available at:http://www.clinicaltrials.gov/ct/show/NCT00113386?order=1. accessed:March 2007
13)Swiss Institute for Applied Cancer Research. Chemotherapy with or without radiation therapy before surgery in treating patients with stage ⅢA non-small cell lung cancer. 2006. available at:http://www.clinicaltrials.gov/ct/show/NCT00030771?order=1. accessed:March 2007
14)Toloza EM, Harpole L, McCrory DC:Noninvasive staging of non-small cell lung cancer:a review of the current evidence. Chest 123(1 Suppl.):137S-146S, 2003
15)Sachs S, Bilfinger TV, Komaroff E, et al:Increased standardized uptake value in the primary lesion predicts nodal or distant metastases at presentation in lung cancer. Clin Lung Cancer 6:310-313, 2005
16)Dhital K, Saunders CA, Seed PT, et al:[(18)F]Fluorodeoxyglucose positron emission tomography and its prognostic value in lung cancer. Eur J Cardiothorac Surg 18:425-428, 2000
17)Jeong HJ, Min JJ, Park JM, et al:Determination of the prognostic value of[(18)F]fluorodeoxyglucose uptake by using positron emission tomography in patients with non-small cell lung cancer. Nucl Med Commun 23:865-870, 2002
18)Vansteenkiste JF, Stroobants SG, Dupont PJ, et al:Prognostic importance of the standardized uptake value on(18)Ffluoro-2-deoxy-glucose-positron emission tomography scan in non-small-cell lung cancer:an analysis of 125 cases. Leuven Lung Cancer Group. J Clin Oncol 17:3201-3206, 1999
19)Lardinois D, Weder W, Hany TF, et al:Staging of non-smallcell lung cancer with integrated positron-emission tomography and computed tomography. N Engl J Med 348:2500-2507, 2003
20)Cerfolio RJ, Bryant AS, Ojha B, et al:Improving the inaccuracies of clinical staging of patients with NSCLC:a prospective trial. Ann Thorac Surg 80:1207-1214, 2005
21)Cerfolio RJ, Ojha B, Bryant AS, et al:The accuracy of integrated PET-CT compared with dedicated PET alone for the staging of patients with nonsmall cell lung cancer. Ann Thorac Surg 78:1017-1023, 2004
22)Hürtgen M, Friedel G, Toomes H, et al:Radical video-assisted mediastinoscopic lymphadenectomy(VAMLA)―technique and first results. Eur J Cardiothorac Surg 21:348-351, 2002
23)Leschber G, Holinka G, Linder A:Video-assisted mediastinoscopic lymphadenectomy(VAMLA)―a method for systematic mediastinal lymphnode dissection. Eur J Cardiothorac Surg 24:192-195, 2003
24)Witte B, Wolf M, Huertgen M, et al:Video-assisted mediastinoscopic surgery:clinical fesibility and accuracy of mediastinal lymph node staging. Ann Thorac Surg 82:1821-1827, 2006
25)Kuzdzal J, Zielinski M, Papla B, et al:Transcervical extended mediastinal lymphadenectomy―the new operative technique and early results in lung cancer staging. Eur J Cardiothorac Surg 27:384-390, 2005
26)Kuzdzal J, Zielinski M, Papla B, et al:The transcervical extended mediastinal lymphadenectomy versus cervical mediastinoscopy in non-small cell lung cancer staging. Eur J Cardiothorac Surg 31:88-94, 2007
27)Annema JT, Versteegh MI, Veselic M, et al:Endoscopic ultrasound added to mediastinoscopy for preoperative staging of patients with lung cancer. JAMA 294:931-936, 2005
28)Larsen SS, Vilmann P, Krasnik M, et al:Endoscopic ultrasound guided biopsy performed routinely in lung cancer staging spares futile thoracotomies:preliminary results from a randomised clinical trial. Lung Cancer 49:377-385, 2005
29)Eloubeidi MA, Cerfolio RJ, Chen VK, et al:Endoscopic ultrasound-guided fine needle aspiration of mediastinal lymph node in patients with suspected lung cancer after positron emission tomography and computed tomography scans. Ann Thorac Surg 79:263-268, 2005
30)Yasufuku K, Chiyo M, Sekine Y, et al:Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes. Chest 126:122-128, 2004
31)Rintoul RC, Skwarski KM, Murchison JT, et al:Endobronchial and endoscopic ultrasound-guided real-time fine-needle spiration for mediastinal staging. Eur Respir J 25:416-421, 2005
32)Yasufuku K, Chiyo M, Koh E, et al:Endobronchial ultrasound guided transbronchial needle aspiration for staging of lung cancer. Lung Cancer 50:347-354, 2005
33)Herth FJ, Ernst A, Eberhardt R, et al:Endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes in the radiologically normal mediastinum. Eur Respir J 28:910-914, 2006
34)Vilmann P, Krasnik M, Larsen SS, et al:Transesophageal endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA)and endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA)biopsy:a combined approach in the evaluation of mediastinal lesions. Endoscopy 37:833-839, 2005
35)Patelli M, Agli LL, Poletti V, et al:Role of fiberscopic transbronchial needle aspiration in the staging of N2 disease due to non-small cell lung cancer. Ann Thorac Surg 73:407-411, 2002
36)Massard G, Ducrocq X, Kochetkova EA, et al:Sampling or node dissection for intraoperative staging of lung cancer:a multicentric cross-sectional study. Eur J Cardiothorac Surg 30:164-167, 2006
37)Non-small Cell Lung Cancer Collaborative Group:Chemotherapy in non-small cell lung cancer:a meta-analysis using updated data on individual patients from 52 randomised clinical trials. BMJ 311:899-909, 1995
38)Arriagada R, Bergman B, Dunant A, et al:Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N Engl J Med 350:351-360, 2004
39)Kato H, IchinoseY, Ohta M, et al:Arandomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung. N Engl J Med 350:1713-1721, 2004
40)Strauss GM, Herndon JE, Maddaus MA, et al:Adjuvant chemotherapy in stage ⅠB non-small cell lung cancer(NSCLC):update of Cancer and Leukemia Group B(CALGB)protocol 9633. ASCO Annual Meeting Proceedings Part Ⅰ. Vol 24(June 20 Supplement). J Clin Oncol 2006;7007
41)Winton TL, Livingston R, Johnson D, et al:A prospective randomised trial of adjuvant vinorelbine(VIN)and cisplatin(CIS)in completely resected stage 1B and Ⅱ non small cell lung cancer(NSCLC)Intergroup JBR. 10[Abstract 7018]. Proc Am Soc Clin Oncol 22:621s, 2004
42)Scagliotti GV, Fossati R, Torri V, et al:Randomized study of adjuvant chemotherapy for completely resected stage Ⅰ, Ⅱ, or ⅢA non-small-cell lung cancer. J Natl Cancer Inst 95:1453-1461, 2003
43)Pignon JP, Tribodet H, Scagliotti GV, et al:Lung Adjuvant Cisplatin Evaluation(LACE):a pooled analysis of five randomized clinical trials including 4,584 patients. ASCO Annual Meeting Proceedings Part Ⅰ. Vol 24(June 20 Supplement). J Clin Oncol 2006;7008
44)Allen MS, Darling GE, Pechet TTV, et al:Morbidity and mortality of major pulmonary resections in patients with early-stage lung cancer:initial results of the randomized, prospective ACOSOG Z0030 trial. Ann Thorac Surg 81:1013-1020, 2006
45)Wu Y, Huang ZF, Wang SY, et al:A randomized trial of systematic nodal dissection in resectable non-small cell lung cancer. Lung Cancer 36:1-6, 2002
46)Stamatis G, Fechner S, Hillejan L, et al:Repeatmediastinoscopy as a restaging procedure. Pneumologie 59:862-866, 2005
47)JaklitschMT, Gu L, HarpoleDH, et al:Prospective phase Ⅱ trial of pre-resection thoracoscopic(VATS)restaging following neoadjuvant therapy for ⅢA(N2)non-small cell lung cancer(NSCLC):results of CALGB 39803. ASCO Annual Meeting Proceedings. Vol 23(June 1 Supplement). J Clin Oncol 2005;7065
48)De Leyn P, Stroobants S, De Wever W, et al:Prospective comparative study of integrated positron emission tomography-computed tomography scan compared with remediastinoscopy in the assessment of residual mediastinal lymph node disease after induction chemotherapy for mediastinoscopy-proven stage ⅢA-N2 non-small-cell lung cancer:a Leuven Lung Cancer Group study. J Clin Oncol 24:3333-3339, 2006
49)Mateu-Navarro M, Rami-Porta R, Bastus-Piulats R, et al:Remediastinoscopy after induction chemotherapy in non-small cell lung cancer. Ann Thorac Surg 70:391-395, 2000
50)Van Schil P, van der Schoot J, Poniewierski J, et al:Remediastinoscopy after neoadjuvant therapy for non-small cell lung cancer. Lung Cancer 37:281-285, 2002
51)De Waele M, Hendriks J, Lauwers P, et al:Nodal status at repeat mediastinoscopy determines survival in non-small cell lung cancer with mediastinal nodal involvement, treated by induction therapy. Eur J Cardiothorac Surg 29:240-243, 2006
52)Cerfolio RJ, Bryant AS, Ojha B:Restaging patients with N2(stage Ⅲa)non-small cell lung cancer after neoadjuvant chemoradiotherapy:a prospective study. J Thorac Cardiovasc Surg 131:1229-1235, 2006