臨床外科65巻11号

2010年10月発行

特集 外科医のための大腸癌の診断と治療

1．大腸癌の基礎

分子生物学からみた大腸癌の発生

著者： 山本英一郎¹ 鈴木拓¹ 豊田実¹ 今井浩三²³

所属機関： ¹札幌医科大学生化学講座 ²東京大学医科学研究所先端医療研究センター ³東京大学医科学研究所附属病院

ページ範囲：P.22 - P.27

文献概要

■大腸癌の発生においてはジェネティック，エピジェネティックな異常が密接に関連する．

■新たな発癌経路としてのserrated pathwayが提唱されている．

■癌幹細胞を標的とする画期的な治療法の開発が期待されている．

参考文献

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