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臨床外科65巻4号

2010年04月発行

文献概要

特集 消化器癌neoadjuvant chemotherapyの新展開 〔根治性向上〕

進行食道癌に対するneoadjuvant chemoradiotherapyの意義

著者: 竹内裕也1 大山隆史1 才川義朗1 北川雄光1

所属機関: 1慶應義塾大学医学部外科

ページ範囲:P.472 - P.477

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要旨:これまで食道癌に対する術前,術後補助療法の有用性を検証したランダム化比較試験(RCT)は数多くみられるものの,研究デザインや治療レジメン,手術精度などの違いから一定の見解は得られていない.しかし最近のmeta-analysisの結果からは術前補助化学療法,術前補助化学放射線療法の有用性も示されるようになっている.わが国における術前補助化学放射線療法の意義については未だ明らかでないが,欧米での標準治療になりつつあるtri-modality therapyとの比較という見地からも,JCOG9907に続く臨床試験として術前補助化学放射線療法を検証する国内多施設共同研究の計画,実行が期待される.

参考文献

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掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1278

印刷版ISSN:0386-9857

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