文献詳細
特集 外科医のための最新癌薬物療法
Ⅰ章 臓器別薬物療法
文献概要
術後補助療法の適応とレジメン選択
小細胞癌治療の主体は全身化学療法と放射線治療であり,手術療法のもつ効果は限られているため,本稿では非小細胞肺癌完全切除例に対する補助療法に話題を絞って提示する.
小細胞癌治療の主体は全身化学療法と放射線治療であり,手術療法のもつ効果は限られているため,本稿では非小細胞肺癌完全切除例に対する補助療法に話題を絞って提示する.
参考文献
1)PORT Meta-analysis Trialists Group:Postoperative radiotherapy in non-small-cell lung cancer:systematic review and meta-analysis of individual patient data from nine randomized controlled trials. Lancet 352:257-263, 1998
2)日本肺癌学会(編):EBMの手法による肺癌診療ガイドライン2005年版.金原出版,2005,pp99-102
3)Non-small Cell Lung Cancer Collaborative Group:Chemotherapy in non-small cell lung cancer:a meta-analysis using updated data on individual patients from 52 randomised clinical trials:BMJ 311:899-909, 1995
4)International Adjuvant Lung Cancer Trial Collaborative Group:Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N Engl J Med 350:351-360, 2004
5)Pignon JP, et al:Lung adjuvant cisplatin evaluation(LACE):a pooled analysis of five randomized clinical trials including 4,584 patients. J Clin Oncol 24 suppl:7008, 2006
6)Winton T, et al:Vinorelbine plus Cisplatin vs. Observation in Resected Non-small-Cell Lung Cancer. N Engl J Med 352:2589-2597, 2005
7)Douillard J, et al:Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage ⅠB-ⅢA non-small-cell lung cancer(Adjuvant Navelbine International Trialist Assocoation[ANITA]):a randomized controlled trial. Lancet Oncol 7:719-727, 2006
8)Strauss GM, et al:Adjuvant paclitaxel plus carboplatin compared with observation in stage ⅠB non-small-cell lung cancer:CALGB9633 with the cancer and leukemia group B, radiation therapy oncology group, and north central cancer treatment group study groups. J Clin Oncol 26:5043-5049, 2008
9)Kato H, et al:for the Japan Lung Cancer Research Group on Postsurgical Adjuvant Chemotherapy:A randomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung. N Engl J Med 350:1713-1721, 2004
10)Hamada C, et al:Meta-analysis of postoperative adjuvant chemotherapy with tegafur-uracil in non-small-cell lung cancer. J Clin Oncol 23:4999-5006, 2005
11)Hamada C, et al:Effect of postoperative adjuvant chemotherapy with tegafur-uracil on survival in patients with stage ⅠA non-small cell lung cancer:an exploratory analysis from a meta-analysis of six randomized controlled trials. J Thorac Oncol 4:1511-1516, 2009
12)Kelly K, et al:Randomized phase Ⅲ trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-small-cell lung cancer:a Southwest Oncology Group trial. J Clin Oncol 19:3210-3218, 2001
13)Wozniak AJ, et al:Randomized trial comparing cisplatin with cisplatin plus vinorelbine in the treatment of advanced non-small-cell lung cancer:a Southwest Oncology Group study. J Clin Oncol 16:2459-2465, 1998
14)Mori K, et al:Phase Ⅱ study of the combination of vonorelbine and cisplatin in advanced non-small-cell lung cancer. Cancer Chemother Pharmacol 53:129-132, 2004
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