臨床外科66巻5号

2011年05月発行

特集 いま必要な外科治療に関する臨床試験の最新知識 ［領域別］外科治療の臨床試験の問題点と今後の展望

肝細胞癌の外科治療に関する臨床試験

著者： 長谷川潔¹ 菅原寧彦¹ 國土典宏¹

所属機関： ¹東京大学医学部肝胆膵外科

ページ範囲：P.588 - P.595

【ポイント】

◆肝細胞癌は何らかの慢性肝障害を合併し，それが長期予後に影響するため，治療効果の客観的評価が難しい．

◆切除後の高再発率が問題であるが，その経路に肝内転移と二次発癌が存在することが課題の克服を困難にしている．

◆客観的に評価する重要性を理解し，他施設や他領域と密な連携を保って，適切にデザインされた試験を完遂することが重要である．

参考文献

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