臨床外科66巻7号

2011年07月発行

特集 術前薬物療法は乳癌手術を縮小させるか

術前分子標的薬療法とセンチネルリンパ節生検

著者： 中村清吾¹

所属機関： ¹昭和大学病院ブレストセンター

ページ範囲：P.892 - P.897

【ポイント】

◆HER2陽性乳癌では，化学療法にトラスツズマブなどの分子標的薬を加えるとpCR率がさらに上昇する．

◆化学療法前に転移陽性のリンパ節も，リンパ節のpCRが得られた場合は郭清が不要となる可能性がある．

◆適切に対象を絞り込めば，センチネルリンパ節の転移陰性率（非郭清率）を高めることが期待される．

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