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雑誌文献

臨床外科67巻11号

2012年10月発行

文献概要

特集 外科医のための癌診療データ 臓器別最新データ 8.膵癌

膵癌の治療

著者: 谷眞至1 山上裕機1

所属機関: 1和歌山県立医科大学第2外科

ページ範囲:P.228 - P.232

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覚えておきたいデータ

◆通常型膵癌切除症例の年代別生存率は2001年以降の症例の1年生存率が63.6%,生存期間中央値が18.2か月と2000年以前と比較して有意に改善している.

◆わが国では積極的に拡大切除が行われてきたが,4編のRCTすべてが拡大郭清による生存期間延長効果はなく,うち2編の下痢の頻度は拡大郭清で42%,48%ときわめて高頻度であった.

◆塩酸ゲムシタビンの補助化学療法としての有用性はCONKO-001試験,JSAP-02試験で報告された.

参考文献

1)日本膵臓学会:膵癌登録報告2007.膵臓22:e1-e429,2007
2)Tempero MA, Arnoletti JP, Behrman S, et al:Pancreatic adenocarcinoma. J Natl Compr Canc Netw 8:972-1017, 2010
3)Pedrazzoli S, DiCarlo V, Dionigi R, et al:Standard versus extended lymphadenectomy associated with pancreatoduodenectomy in the surgical treatment of adenocarcinoma of the head of the pancreas:a multicenter, prospective, randomized study. Lymphadenectomy Study Group. Ann Surg 228:508-517, 1998
4)Yeo CJ, Cameron JL, Lillemoe KD, et al:Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma, part 2:randomized controlled trial evaluating survival, morbidity, and mortality. Ann Surg 236:355-366, 2002
5)Farnell MB, Pearson RK, Sarr MG, et al:A prospective randomized trial comparing standard pancreatoduodenectomy with pancreatoduodenectomy with extended lymphadenectomy in resectable pancreatic head adenocarcinoma. Surgery 138:618-628, 2005
6)Nimura Y, Nagino M, Takao S, et al:Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas:long-term results of a Japanese multicenter randomized controlled trial. J Hepatobiliary Pancreat Sci 19:230-241, 2012
7)Kanda M, Fujii T, Sahin TT, et al:Invasion of the splenic artery is a crucial prognostic factor in carcinoma of the body and tail of the pancreas. Ann Surg 251:483-487, 2010
8)Hirano S, Kondo S, Hara T, et al:Distal pancreatectomy with en bloc celiac axis resection for locally advanced pancreatic body cancer:long-term results. Ann Surg 246:46-51, 2007
9)Kawai M, Kondo S, Yamaue H, et al:Predictive risk factors for clinically relevant pancreatic fistula analyzed in 1,239 patients with pancreaticoduodenectomy:multicenter data collection as a project study of pancreatic surgery by the Japanese Society of Hepato-Biliary-Pancreatic Surgery. J Hepatobiliary Pancreat Sci 18:601-608, 2011
10)Tani M, Kawai M, Hirono S, et al:Use of omentum or falciform ligament does not decrease complications after pancreaticoduodenectomy:nationwide survey of the Japanese Society of Pancreatic Surgery. Surgery 151:183-191, 2012
11)Gooiker GA, van Gijn W, Wouters MW, et al:Systematic review and meta-analysis of the volume-outcome relationship in pancreatic surgery. Br J Surg 98:485-494, 2011
12)Yeo CJ, Cameron JL, Maher MM, et al:A prospective randomized trial of pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy. Ann Surg 222:580-588, 1995
13)Bassi C, Falconi M, Molinari E, et al:Reconstruction by pancreaticojejunostomy versus pancreaticogastrostomy following pancreatectomy:results of a comparative study. Ann Surg 242:767-771, discussion 771-773, 2005
14)Duffas JP, Suc B, Msika S, et al:A controlled randomized multicenter trial of pancreatogastrostomy or pancreatojejunostomy after pancreatoduodenectomy. Am J Surg 189:720-729, 2005
15)Fernández-Cruz L, Cosa R, Blanco L, et al:Pancreatogastrostomy with gastric partition after pylorus-preserving pancreatoduodenectomy versus conventional pancreatojejunostomy:a prospective randomized study. Ann Surg 248:930-938, 2008
16)Bassi C, Falconi M, Molinari E, et al:Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy:results of a prospective randomized trial. Surgery 134:766-771, 2003
17)Berger AC, Howard TJ, Kennedy EP, et al:Does type of pancreaticojejunostomy after pancreaticoduodenectomy decrease rate of pancreatic fistula? A randomized, prospective, dual-institution trial. J Am Coll Surg 208:738-747, 2009
18)Roder JD, Stein HJ, Bottcher KA, et al:Stented versus nonstented pancreaticojejunostomy after pancreatoduodenectomy:a prospective study. Ann Surg 229:41-48, 1999
19)Winter JM, Cameron JL, Campbell KA, et al:Does pancreatic duct stenting decrease the rate of pancreatic fistula following pancreaticoduodenectomy? Results of a prospective randomized trial. J Gastrointest Surg 10:1280-1290, 2006
20)Poon RT, Fan ST, Lo CM, et al:External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreaticoduodenectomy:a prospective randomized trial. Ann Surg 246:425-433, 2007
21)Tani M, Kawai M, Hirono S, et al:A prospective randomized controlled trial of internal versus external drainage with pancreaticojejunostomy for pancreaticoduodenectomy. Am J Surg 199:759-764, 2010
22)Pessaux P, Sauvanet A, Mariette C, et al:External pancreatic duct stent decreases pancreatic fistula rate after pancreaticoduodenectomy:prospective multicenter randomized trial. Ann Surg 253:879-885, 2011
23)Motoi F, Egawa S, Rikiyama T, et al:Randomized clinical trial of external stent drainage of the pancreatic duct to reduce postoperative pancreatic fistula after pancreaticojejunostomy. Br J Surg 99:524-531, 2012
24)Diener MK, Seiler CM, Rossion I, et al:Efficacy of stapler versus hand-sewn closure after distal pancreatectomy(DISPACT):a randomised, controlled multicentre trial. Lancet 377:1514-1522, 2011
25)Neoptolemos JP, Stocken DD, Friess H, et al:A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med 350:1200-1210, 2004
26)Neoptolemos JP, Stocken DD, Tudur Smith C, et al:Adjuvant 5-fluorouracil and folinic acid vs observation for pancreatic cancer:composite data from the ESPAC-1 and-3(v1)trials. Br J Cancer 100:246-250, 2009
27)Neoptolemos JP, Stocken DD, Bassi C, et al:Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection:a randomized controlled trial. JAMA 304:1073-1081, 2010
28)Oettle H, Post S, Neuhaus P, et al:Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer:a randomized controlled trial. JAMA 297:267-277, 2007
29)Ueno H, Kosuge T, Matsuyama Y, et al:A randomised phase Ⅲ trial comparing gemcitabine with surgery-only in patients with resected pancreatic cancer:Japanese Study Group of Adjuvant Therapy for Pancreatic Cancer. Br J Cancer 101:908-915, 2009

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1278

印刷版ISSN:0386-9857

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