臨床外科68巻12号

2013年11月発行

特集 漢方を上手に使う―エビデンスに基づいた外科診療

周術期管理・合併症と漢方

黄疸・肝障害―茵蔯蒿湯

著者： 海保隆¹ 柳澤真司¹ 新村兼康¹ 岡本亮¹ 西村真樹¹ 小林壮一¹ 岡庭輝¹ 柴田涼平¹ 松尾めぐみ¹ 土屋俊一¹

所属機関： ¹君津中央病院外科

ページ範囲：P.1308 - P.1313

文献概要

【ポイント】

◆茵蔯蒿湯はウルソデオキシコール酸と異なり，胆汁酸非依存性の胆汁分泌を促進する．よって胆汁うっ滞を呈する病態ではウルソデオキシコール酸との併用は合目的的である．

◆外科領域では先天性胆道閉鎖症の術後，減黄不良の閉塞性黄疸患者，大量肝切除患者の術後高ビリルビン血症などに有用である．

◆肝切除患者の周術期に大建中湯と併用することにより，術後残肝血流の微小循環改善作用が期待される．

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