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雑誌文献

臨床外科68巻3号

2013年03月発行

文献概要

特集 CRT時代の直腸癌手術―最善の戦略は何か 〔CRTに関する諸問題〕

術前CRTのバイオマーカー

著者: 石原聡一郎1 福島慶久1 赤羽根拓弥1 島田竜1 堀内敦1 中村圭介1 端山軍1 山田英樹1 野澤慶次郎1 松田圭二1 橋口陽二郎1 渡邉聡明2

所属機関: 1帝京大学医学部外科 2東京大学医学部腫瘍外科

ページ範囲:P.302 - P.307

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【ポイント】

◆CRTの組織学的効果と末梢血リンパ球の照射によるアポトーシスとの間には相関関係がある.

◆CRTによる副作用(下痢,白血球減少)があった症例や,末梢血好中球が<65%の症例で術後再発は少ない.

◆CRTの効果予測・予後予測のためには,癌と宿主(患者)の両方からのアプローチが必要である.

参考文献

1)石原聡一郎,飯沼久恵,福島慶久,他:直腸癌に対する術前化学放射線療法の効果予測:臨床病理因子の解析と末梢血リンパ球を用いた実験的検討.癌の臨59,2013(印刷中)
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掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1278

印刷版ISSN:0386-9857

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