臨床外科68巻4号

2013年04月発行

特集 「食道胃接合部癌」に迫る！

各論

食道胃接合部腺癌に対する化学放射線療法―欧米におけるこれまでの治療開発とわが国における放射線療法の果たす役割

著者： 長谷川慎一¹² 吉川貴己¹²

所属機関： ¹横浜市立大学外科治療学 ²神奈川県立がんセンター消化器外科

ページ範囲：P.434 - P.439

文献概要

【ポイント】

◆欧米の臨床試験の結果から，切除可能食道胃接合部腺癌に対する術前化学放射線療法は有望な治療戦略であるが，術前化学療法に対する優越性はいまだ明らかではない．

◆術前化学放射線療法は，扁平上皮癌＞腺癌，術前化学療法は，腺癌＞扁平上皮癌と，組織型により治療効果が異なる可能性がある．

◆食道胃接合部腺癌根治切除例の再発形式の検討から，わが国の局所再発は欧米より少なく，補助療法として放射線治療の果たす役割は欧米に比べると相対的に低い可能性がある．

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Esophageal Cancer V.1. 2010, 2010

Gastric Cancer（including cancer in the proximal 5 cm of the stomach）V.2. 2011, 2011