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文献詳細

雑誌文献

臨床外科70巻7号

2015年07月発行

文献概要

特集 Neoadjuvant therapyの最新の動向—がんの治療戦略はどのように変わっていくのか がん種別:術前補助療法の臨床的意義と今後の方向性

胃癌に対するneoadjuvant chemotherapy

著者: 山下裕玄1 瀬戸泰之1

所属機関: 1東京大学医学部附属病院胃食道外科

ページ範囲:P.824 - P.827

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【ポイント】
◆胃切除後の場合には化学療法の忍容性が低下するため,術前に行うほうが用量強度は維持できる.
◆高度リンパ節転移症例に対するneoadjuvant chemotherapyは生存期間を大幅に延長した.
◆腹膜再発の高危険群である大型3型,4型については第Ⅲ相試験の結果待ちであるが,少なくとも手術先行での治療成績が十分でないことからneoadjuvant chemotherapyの効果を期待したい集団である.

参考文献

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15)Sato Y, Takayama T, Sagawa T, et al:Phase Ⅱ study of S-1, docetaxel and cisplatin combination chemotherapy in patients with unresectable metastatic gastric cancer. Cancer Chemother Pharmacol 66:721-728, 2010
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掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1278

印刷版ISSN:0386-9857

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