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臨床外科71巻4号

2016年04月発行

文献概要

特集 大腸癌肝転移—最新の治療ストラテジー 総論

大腸癌肝転移の現状

著者: 江本成伸1 石原聡一郎1 渡邉聡明1

所属機関: 1東京大学腫瘍外科

ページ範囲:P.388 - P.392

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【ポイント】
◆肝臓は大腸癌の転移巣として最も頻度の高い臓器である.
◆肝転移の治療は肝切除,全身化学療法,肝動注療法および熱凝固療法に大別でき,根治切除可能な肝転移には肝切除が推奨される.
◆化学療法の進歩により,切除不能であったものが切除可能にconversionする症例が存在し,長期生存が得られる場合がある.
◆患者の耐術能やPSを考慮して治療方針を決定する必要がある.

参考文献

1)大腸癌研究会(編):大腸癌治療ガイドライン 医師用2014年版,金原出版,2014
2)大腸癌研究会(編):大腸癌治療ガイドライン 医師用2010年版,金原出版,2010
3)大腸癌研究会(編):大腸癌治療ガイドライン 医師用2005年版,金原出版,2005
4)大腸癌研究会(編):大腸癌取扱い規約第8版,金原出版,2013
5)Yamaguchi M, Yamanori A, Igarashi M, et al:A resected case of liver metastasis from colon cancer that occurred 13 years after a colectomy. Hepatogastroenterology 55:2221-2223, 2008
6)Shinto E, Takahashi K, Yamaguchi T, et al:Validation and Modification of the Japanese Classification System for Liver Metastases from Colorectal Cancer:A Multi-institutional Study. Ann Surg Oncol 22:3888-3895, 2015
7)Abdalla EK, Vauthey JN, Ellis LM, et al:Recurrence and outcomes following hepatic resection, radiofrequency ablation, and combined resection/ablation for colorectal liver metastases. Ann Surg 239:818-825;discussion 825-817, 2004
8)Kato T, Yasui K, Hirai T, et al:Therapeutic results for hepatic metastasis of colorectal cancer with special reference to effectiveness of hepatectomy:analysis of prognostic factors for 763 cases recorded at 18 institutions. Dis Colon Rectum 46:S22-31, 2003
9)Lam VW, Spiro C, Laurence JM, et al:A systematic review of clinical response and survival outcomes of downsizing systemic chemotherapy and rescue liver surgery in patients with initially unresectable colorectal liver metastases. Ann Surg Oncol 19:1292-1301, 2012
10)Adam R:Developing strategies for liver metastases from colorectal cancer. Semin Oncol 34:S7-11, 2007
11)Bismuth H, Adam R, Levi F, et al:Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy. Ann Surg 224:509-520;discussion 520-502, 1996
12)Choti MA, Sitzmann JV, Tiburi MF, et al:Trends in long-term survival following liver resection for hepatic colorectal metastases. Ann Surg 235:759-766, 2002
13)Adam R, Delvart V, Pascal G, et al:Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy:a model to predict long-term survival. Ann Surg 240:644-657;discussion 657-648, 2004
14)Adam R, Wicherts DA, de Haas RJ, et al:Patients with initially unresectable colorectal liver metastases:is there a possibility of cure? J Clin Oncol 27:1829-1835, 2009
15)Ychou M, Hohenberger W, Thezenas S, et al:A randomized phase Ⅲ study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer. Ann Oncol 20:1964-1970, 2009
16)Mitry E, Fields AL, Bleiberg H, et al:Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer:a pooled analysis of two randomized trials. J Clin Oncol 26:4906-4911, 2008
17)Portier G, Elias D, Bouche O, et al:Multicenter randomized trial of adjuvant fluorouracil and folinic acid compared with surgery alone after resection of colorectal liver metastases:FFCD ACHBTH AURC 9002 trial. J Clin Oncol 24:4976-4982, 2006
18)Kanemitsu Y, Kato T, Shimizu Y, et al:A randomized phase Ⅱ/Ⅲ trial comparing hepatectomy followed by mFOLFOX6 with hepatectomy alone as treatment for liver metastasis from colorectal cancer:Japan Clinical Oncology Group Study JCOG0603. Jpn J Clin Oncol 39:406-409, 2009
19)NCCN Clinical Practice Guidelines in Oncology:Colon Cancer Version 2, 2015(2015)
20)NCCN Clinical Practice Guidelines in Oncology:Rectal Cancer Version 2, 2015(2015)
21)Maughan TS, Adams RA, Smith CG, et al:Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer:results of the randomised phase 3 MRC COIN trial. Lancet 377:2103-2114, 2011
22)Primrose J, Falk S, Finch-Jones M, et al:Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis:the New EPOC randomised controlled trial. Lancet Oncol 15:601-611, 2014
23)Venook AP, Niedzwiecki D, Lenz HJ:CALGB/SWOG 80405:Phase Ⅲ trial of irinotecan/5-FU/leucovorin(FOLFIRI)or oxaliplatin/5-FU/leucovorin(mFOLFOX6)with bevacizumab(BV)or cetuximab(CET)for patients(pts)with KRAS wild-type(wt)untreated metastatic adenocarcinoma of the colon or rectum(MCRC). J Clin Oncol, 2014 ASCO Annual Meeting Abstracts 32, LBA3(2014)
24)Schmoll HJ, Van Cutsem E, Stein A, et al:ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making. Ann Oncol 23:2479-2516, 2012
25)Van Cutsem E, Cervantes A, Nordlinger B, et al:Metastatic colorectal cancer:ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 25(Suppl 3):iii1-9, 2014

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1278

印刷版ISSN:0386-9857

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