icon fsr

文献詳細

雑誌文献

臨床外科71巻4号

2016年04月発行

文献概要

特集 大腸癌肝転移—最新の治療ストラテジー 治療の実際

肝切除

著者: 酒井望1 清水宏明1 大塚将之1 加藤厚1 吉富秀幸1 古川勝規1 高屋敷吏1 高野重紹1 久保木知1 鈴木大亮1 賀川真吾1 野島広之1 宮崎勝1

所属機関: 1千葉大学大学院臓器制御外科学

ページ範囲:P.409 - P.416

文献購入ページに移動
【ポイント】
◆大腸癌肝転移治療のgold standardは外科的切除であり,血管合併切除,門脈塞栓術などを併用し治癒切除することで予後の改善に寄与しうる.
◆肝再発,肺再発症例においても,治癒切除可能であればその予後は非切除群に対し良好であり,積極的に切除を考慮すべきである.
◆切除の可否,治療プラン決定にあたっては,肝臓外科医を含めたmultidisciplinary teamにより総合的に判断されるべきである.

参考文献

1)Sung JJ, Lau JY, Goh KL, et al;Asia Pacific Working Group on Colorectal C:Increasing incidence of colorectal cancer in Asia:implications for screening. Lancet Oncol 6:871-876, 2005
2)Alberts SR, Horvath WL, Sternfeld WC, et al:Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer:a North Central Cancer Treatment Group phase II study. J Clin Oncol 23:9243-9249, 2005
3)Nordlinger B, Van Cutsem E, Rougier P, et al:Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European Colorectal Metastases Treatment Group. Eur J Cancer 43:2037-2045, 2007
4)Van den Eynde M, Hendlisz A:Treatment of colorectal liver metastases:a review. Rev Recent Clin Trials 4:56-62, 2009
5)Adam R, De Gramont A, Figueras J, et al:The oncosurgery approach to managing liver metastases from colorectal cancer:a multidisciplinary international consensus. Oncologist 17:1225-1239, 2012
6)Spolverato G, Ejaz A, Azad N, et al:Surgery for colorectal liver metastases:The evolution of determining prognosis. World J Gastrointest Oncol 5:207-221, 2013
7)Abdalla EK, Vauthey JN:Improved survival after resection of colorectal liver metastases. J Clin Oncol 24:2679;author reply 2680-2671, 2006
8)Karoui M, Vigano L, Goyer P, et al:Combined first-stage hepatectomy and colorectal resection in a two-stage hepatectomy strategy for bilobar synchronous liver metastases. Br J Surg 97:1354-1362, 2010
9)Tsim N, Healey AJ, Frampton AE, et al:Two-stage resection for bilobar colorectal liver metastases:R0 resection is the key. Ann Surg Oncol 18:1939-1946, 2011
10)Homayounfar K, Bleckmann A, Conradi LC, et al:Bilobar spreading of colorectal liver metastases does not significantly affect survival after R0 resection in the era of interdisciplinary multimodal treatment. Int J Colorectal Dis 27:1359-1367, 2012
11)Schnitzbauer AA, Lang SA, Goessmann H, et al:Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings. Ann Surg 255:405-414, 2012
12)Kokudo N, Tada K, Seki M, et al:Anatomical major resection versus nonanatomical limited resection for liver metastases from colorectal carcinoma. Am J Surg 181:153-159, 2001
13)Liu W, Sun Y, Zhang L, et al:Negative surgical margin improved long-term survival of colorectal cancer liver metastases after hepatic resection:a systematic review and meta-analysis. Int J Colorectal Dis 30:1365-1373, 2015
14)Andreou A, Aloia TA, Brouquet A, et al:Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy. Ann Surg 257:1079-1088, 2013
15)de Haas RJ, Wicherts DA, Flores E, et al:R1 resection by necessity for colorectal liver metastases:is it still a contraindication to surgery? Ann Surg 248:626-637, 2008
16)Makuuchi M, Thai BL, Takayasu K, et al:Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma:a preliminary report. Surgery 107:521-527, 1990
17)Abulkhir A, Limongelli P, Healey AJ, et al:Preoperative portal vein embolization for major liver resection:a meta-analysis. Ann Surg 247:49-57, 2008
18)de Graaf W, van Lienden KP, van den Esschert JW, et al:Increase in future remnant liver function after preoperative portal vein embolization. Br J Surg 98:825-834, 2011
19)Wicherts DA, de Haas RJ, Salloum C, et al:Repeat hepatectomy for recurrent colorectal metastases. Br J Surg 100:808-818, 2013
20)Kulik U, Bektas H, Klempnauer J, et al:Repeat liver resection for colorectal metastases. Br J Surg 100:926-932, 2013
21)Takahashi M, Hasegawa K, Oba M, et al:Repeat resection leads to long-term survival:analysis of 10-year follow-up of patients with colorectal liver metastases. Am J Surg 210:904-910, 2015
22)Oba M, Hasegawa K, Matsuyama Y, et al:Discrepancy between recurrence-free survival and overall survival in patients with resectable colorectal liver metastases:a potential surrogate endpoint for time to surgical failure. Ann Surg Oncol 21:1817-1824, 2014
23)Ambiru S, Miyazaki M, Ito H, et al:Resection of hepatic and pulmonary metastases in patients with colorectal carcinoma. Cancer 82:274-278, 1998
24)Hwang M, Jayakrishnan TT, Green DE, et al:Systematic review of outcomes of patients undergoing resection for colorectal liver metastases in the setting of extra hepatic disease. Eur J Cancer 50:1747-1757, 2014
25)Sourrouille I, Mordant P, Maggiori L, et al:Long-term survival after hepatic and pulmonary resection of colorectal cancer metastases. J Surg Oncol 108:220-224, 2013
26)Tsukamoto S, Kinugasa Y, Yamaguchi T, et al:Survival after resection of liver and lung colorectal metastases in the era of modern multidisciplinary therapy. Int J Colorectal Dis 29:81-87, 2014
27)Matsui T, Kitamura T, Ozawa H, et al:Analysis of treatment that includes both hepatic and pulmonary resections for colorectal metastases. Surg Today 44:702-711, 2014
28)Kamiyoshihara M, Igai H, Kawatani N, et al:Lung metastasectomy for postoperative colorectal cancer in patients with a history of hepatic metastasis. Gen Thorac Cardiovasc Surg 62:314-320, 2014
29)Mise Y, Kopetz S, Mehran RJ, et al:Is complete liver resection without resection of synchronous lung metastases justified? Ann Surg Oncol 22:1585-1592, 2015
30)Dave RV, Pathak S, White AD, et al:Outcome after liver resection in patients presenting with simultaneous hepatopulmonary colorectal metastases. Br J Surg 102:261-268, 2015
31)Andres A, Mentha G, Adam R, et al:Surgical management of patients with colorectal cancer and simultaneous liver and lung metastases. Br J Surg 102:691-699, 2015
32)Malde DJ, Khan A, Prasad KR, et al:Inferior vena cava resection with hepatectomy:challenging but justified. HPB(Oxford)13:802-810, 2011
33)Miyazaki M, Ito H, Nakagawa K, et al:Aggressive surgical resection for hepatic metastases involving the inferior vena cava. Am J Surg 177:294-298, 1999
34)Yoshidome H, Takeuchi D, Ito H, et al:Should the inferior vena cava be reconstructed after resection for malignant tumors? Am J Surg 189:419-424, 2005
35)Yoshidome H, Kimura F, Shimizu H, et al:Interval period tumor progression:does delayed hepatectomy detect occult metastases in synchronous colorectal liver metastases? J Gastrointest Surg 12:1391-1398, 2008
36)Folprecht G, Gruenberger T, Bechstein WO, et al:Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab:the CELIM randomised phase 2 trial. Lancet Oncol 11:38-47, 2010

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1278

印刷版ISSN:0386-9857

雑誌購入ページに移動
icon up
あなたは医療従事者ですか?