1)Kaiho T, Tanaka T, Tsuchiya S, et al:Effect of the herbal medicine Dai-kenchu-to for serum ammonia in hepatectomized patients. Hepatogastroenterology 52:161-5, 2004
2)Nishi M, Shimada M, Uchiyama H, et al:The beneficial effects of Kampo medicine Dai-ken-chu-to after hepatic resection:a prospective randomized control study. Hepatogastroenterology 59:2290-2294, 2012
3)Katsuno H, Maeda K, Kaiho T, et al:Clinical efficacy of Daikenchuto for gastrointestinal dysfunction following colon surgery:a randomized, double-blind, multi-center, placebo-controlled study(JFMC39-0902). Jpn J Clin Oncol 45:650-656, 2015
4)Shimada M, Morine Y, Nagano H, et al:Effect of TU-100, a traditional Japanese medicine, administered after hepatic resection in patients with liver cancer:a multi-center, phase Ⅲ triral(JFMC40-1001). Int J Clin Oncol 20:95-104, 2015
5)Yoshikawa K, Shimada M, Wakabayashi G, et al:Effect of Daikenchuto, a Traditional Japanese Herbal Medicine, after Total Gastrectomy for Gastric Cancer:A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase Ⅱ Trial. J Am Coll Surg 221:571-578, 2015
6)Kono T, Hata T, Morita S, et al:Goshajinkigan oxaliplatin neurotoxicity evaluation(GONE):a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy. Cancer Chemother Pharmacol 72:1283-1290, 2013
7)Nishioka M, Shimada M, Kurita N, et al:The Kampo medicine, Goshajinkigan, prevents neuropathy in patients treated by FOLFOX regimen. Int J Clin Oncol 16:322-327, 2011
8)Oki E, Emi Y, Kojima H, et al:Preventive effect of Goshajinkigan on peripheral neurotoxicity of FOLFOX therapy(GENIUS trial):a placebo-controlled, double-blind, randomized phase Ⅲ study. Int J Clin Oncol 20:767-775, 2015
9)Matsuda C, Munemoto Y, Mishima H, et al:Double-blind, placebo-controlled, randomized phase Ⅱ study of TJ-14(Hangeshashinto)for infusional fluorinated-pyrimidine-based colorectal cancer chemotherapy-induced oral mucositis. Cancer Chemother Pharmacol 76:97-103, 2015
10)Ikemoto T, Shimada M, Iwahashi S, et al:Changes of immunological parameters with administration of Japanese Kampo medicine(Juzen-Taihoto/TJ-48)in patients with advanced pancreatic cancer. Int J Clin Oncol 19:81-86, 2014