icon fsr

文献詳細

雑誌文献

臨床外科73巻12号

2018年11月発行

文献概要

特集 炎症性腸疾患アップデート—いま外科医に求められる知識と技術 押さえておくべき知識

炎症性腸疾患の疫学

著者: 吉田康祐1 水野慎大1 金井隆典1

所属機関: 1慶應義塾大学医学部消化器内科

ページ範囲:P.1310 - P.1314

文献購入ページに移動
【ポイント】
◆潰瘍性大腸炎およびクローン病を指す炎症性腸疾患は増加傾向にあり,2016年度の集計では潰瘍性大腸炎は167,872人,クローン病は42,789人が特定疾患の給付対象にある.
◆潰瘍性大腸炎は20〜60歳台にかけて幅広い年代でみられ,クローン病は20〜40歳台にピークがみられる.
◆治療の進歩により手術回避可能な症例があるものの,依然手術が必要な場合は多い.一方で腸管の発癌リスクは高く,長期経過例は注意を要する.

参考文献

1)Ananthakrishnan AN:Epidemiology and risk factors for IBD. Nat Rev Gastroenterol Hepatol 12:205-217, 2015
2)守田則一,広橋紀正,中村 一,他:IBDの全国疫学調査(第1報・第2報):潰瘍性大腸炎の疫学的研究.厚生省特定疾患難治性炎症性腸管障害調査研究班 平成4年度研究報告書,1992
3)衛生行政報告例の概況(http://www.mhlw.go.jp/toukei/list/36-19a.html)
4)難病情報センターHP特定疾患医療受給者証所持者数より(http://www.nanbyou.or.jp/entry/1356)
5)政府統計の総合窓口(e-Stat)衛生報告例より(https://www.e-stat.go.jp/)
6)Höie O, Wolters F, Riis L, et al:Ulcerative colitis:patient characteristics may predict 10-yr disease recurrence in a European-wide population-based cohort. Am J Gastroenterol 102:1692-1701, 2007
7)Ha CY, Newberry RD, Stone CD, et al:Patients with late-adult-onset ulcerative colitis have better outcomes than those with early onset disease. Clin Gastroenterol Hepatol 8:682-687. e1, 2010
8)Colombel JF, Rutgeerts P, Reinisch W, et al:Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis. Gastroenterology 141:1194-1201, 2011
9)Gower-Rousseau C, Dauchet L, Vernier-Massouille G, et al:The natural history of pediatric ulcerative colitis:a population-based cohort study. Am J Gastroenterol 104:2080-2088, 2009
10)Allison J, Herrinton LJ, Liu L, et al:Natural history of severe ulcerative colitis in a community-based health plan. Clin Gastroenterol Hepatol 6:999-1003, 2008
11)Solberg IC, Lygren I, Jahnsen J, et al:Clinical course during the first 10 years of ulcerative colitis:results from a population-based inception cohort(IBSEN Study). Scand J Gastroenterol 44:431-440, 2009
12)Solberg IC, Vatn MH, Høie O, et al:Clinical course in Crohn's disease:results of a Norwegian population-based ten-year follow-up study. Clin Gastroenterol Hepatol 5:1430-1438, 2007
13)Frolkis AD, Dykeman J, Negrón ME, et al:Risk of surgery for inflammatory bowel diseases has decreased over time:a systematic review and meta-analysis of population-based studies. Gastroenterology 145:996-1006, 2013
14)Vermeire S, van Assche G, Rutgeerts P:Review article:Altering the natural history of Crohn's disease—evidence for and against current therapies. Aliment Pharmacol Ther 25:3-12, 2007
15)Sutherland LR, Ramcharn S, Bryant H, et al:Effect of Cigarette Smoking on Recurrence of Crohn's Disease. Gastroenterology 98:1123-1128, 1990
16)Eaden JA, Abrams KR, Mayberry JF:The risk of colorectal cancer in ulcerative colitis:a meta-analysis. Gut 48:526-535, 2001
17)Rutter MD, Saunders BP, Wilkinson KH, et al:Thirty-year analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis Gastroenterology 130:1030-1038, 2006
18)Ekbom A, Helmick C, Zack M, et al:Ulcerative colitis and colorectal cancer. A population-based study. N Engl J Med 323:1228-1233, 1990
19)Baker WN, Glass RE, Ritchie JK, et al:Cancer of the rectum following colectomy and ileorectal anastomosis for ulcerative colitis Br J Surg 65:862-868, 1978
20)Magro F, Gionchetti P, Eliakim R, et al:Third European evidence-based consensus on diagnosis and management of ulcerative colitis. part 1:definitions, diagnosis, extra-intestinal manifestations, pregnancy, cancer surveillance, surgery, and ileo-anal pouch disorders. J Crohns Colitis 11:649-670, 2017
21)Ekbom A, Helmick C, Zack M, et al:Increased risk of large-bowel cancer in Crohn's disease with colonic involvement. Lancet 336:357-359, 1990
22)Jess T, Gamborg M, Matzen P, et al:Increased risk of intestinal cancer in Crohn's disease:a meta-analysis of population-based cohort studies. Am J Gastroenterol 100:2724-2729, 2005
23)Jess T, Gamborg M, Munkholm P, et al:Overall and cause-specific mortality in ulcerative colitis:meta-analysis of population-based inception cohort studies. Am J Gastroenterol 102:609-617, 2007
24)Jess T, Frisch M, Simonsen J:Trends in overall and cause-specific mortality among patients with inflammatory bowel disease from 1982 to 2010. Clin Gastroenterol Hepatol 11:43-48, 2013
25)Bewtra M, Kaiser LM, TenHave T, et al:Crohn's disease and ulcerative colitis are associated with elevated standardized mortality ratios:a meta-analysis. Inflamm Bowel Dis 19:599-613, 2013
26)Canavan C, Abrams KR, Mayberry JF:Meta-analysis:mortality in Crohn's disease. Aliment Pharmacol Ther 25:861-870, 2007

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1278

印刷版ISSN:0386-9857

雑誌購入ページに移動
icon up
あなたは医療従事者ですか?