臨床外科78巻12号

2023年11月発行

特集 胃癌に対するconversion surgery—Stage Ⅳでも治したい！

各論

遠隔転移を有する胃癌治癒切除後に対する術後化学療法

著者： 小倉望¹ 廣瀬俊晴¹ 髙島淳生¹

所属機関： ¹国立がん研究センター中央病院消化管内科

ページ範囲：P.1363 - P.1368

文献概要

【ポイント】
◆遠隔転移を有する胃癌治癒切除（R0）後に対する術後化学療法の有効性を示唆する報告はあるものの，質の高いエビデンスはない．
◆レジメンは，Stage Ⅱ〜Ⅲに対する術後補助化学療法または緩和的薬物療法に準じた報告があるが，エビデンスレベルは低い．手術の影響により全身状態が低下していることも多く，症例ごとに適切なレジメンを選択することが重要である．
◆免疫チェックポイント阻害薬を含んだ周術期治療開発が進んでおり，これらの試験結果が待たれる．

参考文献

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