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雑誌文献

臨床婦人科産科60巻6号

2006年06月発行

文献概要

今月の臨床 性差医療

メタボリックシンドロームと性差

著者: 西澤均1 船橋徹1

所属機関: 1大阪大学大学院医学系研究科内分泌・代謝内科学

ページ範囲:P.866 - P.871

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はじめに

 メタボリックシンドロームの罹患率には明らかな性差があり,男性に多い.その比は診断基準や母集団によって異なるが,男性が3~6倍以上とされている.

参考文献

1)メタボリックシンドローム診断基準検討委員会 : メタボリックシンドロームの定義と診断基準.日本内科学会雑誌94 : 1─16, 2005
2)The IDF consensus worldwide definition of the metabolic syndrome. Available from http : //www.idf.org/webdata/docs/IDF_Metasyndrome_definition.pdf[Accessed 16 October 2005]
3)メタボリックシンドローム診療ガイダンス,メジカルビュー社,38頁,53頁
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14) Kumada M, Kihara S, Sumitsuji S, et al : Osaka CAD Study Group. Coronary artery disease : Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 23 : 85─89, 2003
15) Ryo M, Nakamura T, Kihara S, et al : Adiponectin as a biomarker of the metabolic syndrome. Circ J 68 : 975─981, 2004
16) Nishizawa H, Shimomura I, Kishida K, et al : Androgens decrease plasma adiponectin, an insulin─sensitizing adipocyte─derived protein. Diabetes 51 : 2734─2741, 2002
17) Tsou PL, Jiang YD, Chang CC, et al : Sex─related differences between adiponectin and insulin resistance in schoolchildren. Diabetes Care 27 : 308─313, 2004
18) Bottner A, Kratzsch J, Muller G, et al : Gender differences of adiponectin levels develop during the progression of puberty and are related to serum androgen levels? J Clin Endocrinol Metab 89 : 4053─4061, 2004
19) Xu A, Chan KW, Hoo RL, et al : Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes. J Biol Chem 280 : 18073─18080, 2005

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1294

印刷版ISSN:0386-9865

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