臨床婦人科産科60巻9号

2006年09月発行

今月の臨床 PCOS─新たな視点

PCOSに関連した新しい分子，遺伝子

1．アディポネクチン，グレリン

著者： 河野康志¹ 楢原久司¹

所属機関： ¹大分大学医学部産科婦人科学教室

ページ範囲：P.1200 - P.1205

文献概要

はじめに

　多嚢胞性卵巣症候群（polycystic ovary syndrome : PCOS）は排卵障害をきたし，不妊症の原因として重要な疾患である．そのなかにはインスリン抵抗性が認められる症例が存在することから，代謝性疾患と関連することが知られている．近年，肥満や糖代謝に関連した分子がいくつかクローニングされており，その役割が解明されつつある．本稿では，PCOSとインスリン抵抗性に関連した分子としてアディポネクチンおよびグレリンについて述べる．

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