臨床婦人科産科62巻4号

2008年04月発行

今月の臨床 産婦人科臨床の難題を解く─私はこうしている II 不妊治療 【ART】

1.至適な卵巣刺激法とは？

著者： 田村みどり¹ 石塚文平¹

所属機関： ¹聖マリアンナ医科大学産科婦人科

ページ範囲：P.498 - P.501

1 はじめに

　ARTおよび無排卵症に対する調節卵巣刺激（controlled ovarian stimulation : COS）は広く行われている．当院でも，IVFの標準的なプロトコールはlong法のGnRHアゴニスト併用下のゴナドトロピン療法である．今回，特にpoor responderや35歳以上の高齢患者，卵巣過剰刺激症候群（ovarian hyperstimulation syndrome : OHSS）のリスクの高い多嚢胞性卵巣（polycystic ovary : PCO），それぞれについてのCOSのプロトコールについてできるだけ最近の文献で，randomized controlled study（RCT）や規模の大きい試験の報告を参考に調節刺激法を検討した．

参考文献

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18） 倉林　工 : 生殖医療ガイドライン2007（日本生殖医学会編）．pp191─192，金原出版，2007