文献詳細
文献概要
今月の臨床 不育症の診療指針 不育症の治療法
6.ピシバニール療法
著者: 伊藤理廣12
所属機関: 1社会保険群馬中央総合病院産婦人科 2リプロダクションセンター
ページ範囲:P.269 - P.274
文献購入ページに移動●夫リンパ球療法の代替としてピシバニール療法は有用である.
●適応に関してはさまざまな意見があり,まだ一定していない.
●Th17やTregなどの免疫因子が関与している可能性がある.
●適応に関してはさまざまな意見があり,まだ一定していない.
●Th17やTregなどの免疫因子が関与している可能性がある.
参考文献
1) 藤井知行,高見沢勝,川名 尚,他 : 初期習慣流産の夫リンパ球による免疫療法とその評価法に関する研究.日産婦会誌41 : 115─121, 1989
2) Taylor C, Faulk WP : Prevention of recurrent abortion with leucocyte transfusions. Lancet 2 : 68─70, 1981
3) Taylor CG, Faulk WP, McIntyre JA : Prevention of recurrent spontaneous abortions by leukocyte transfusions. J R Soc Med 78 : 623─627, 1985
4) McIntyre JA, Faulk WP, Taylor CG, et al : Immunologic testing and immunotherapy in recurrent spontaneous abortion. Obstet Gynecol 67 : 169─175, 1986
5) Okamoto H, Shoin S, Koshimura S, et al : Studies on the anticancer and streptolysin S-forming abilities of hemolytic streptococci. Jpn J Microbiol 11 : 323─326, 1967
6) Tsukagoshi S, Sakurai Y, Sato H, et al : Tumor-inhibitory effect of a streptococcal preparation(NSC-B116209). Cancer Chemother Rep 56 : 9─17, 1972
7) Katano K, Ogasawara M, Aoki K, et al : Clinical trial of immunostimulation with a biological response modifier in unexplained recurrent spontaneous abortion patients. J Clin Immunol 17 : 472─477, 1997
8) 厚生労働科学研究不育症治療に関する再評価と新たなる治療法の開発に関する研究班を基にした不育症管理に関する提言,2011
9) Caudle MR, Rote NS, Scott JR, et al : Histocompatibility in couples with recurrent spontaneous abortion and normal fertility. Fertil Steril 9 : 793─798, 1983
10) Sbracia M, Mastrone M, Scarpellini F, et al : Influence of histocompatibility antigens in recurrent spontaneous abortion couples and on their reproductive performances. Am J Reprod Immunol 35 : 85─92, 1996
11) Aoki K, Kajiura S,Gleicher N, et al : Preconceptional natural-killer-cell activity as a predictor of miscarriage. Lancet 345 : 1340─1342, 1995
12) Martínez-García EA, Sánchez-Hernández PE, Chavez-Robles B, et al : The Distribution of CD56CD16 and CD56CD16 Cells are Associated with Prolactin Levels during Pregnancy and Menstrual Cycle in Healthy Women. Am J Reprod Immunol 65 : 433─437, 2011
13) Kwak-Kim J, Park JC, Ahn HK, et al : Immunological modes of pregnancy loss. Am J Reprod Immunol 63 : 611─623, 2010
14) Kwak-Kim J, Yang KM, Gilman-Sachs A : Recurrent pregnancy loss : a disease of inflammation and coagulation. J Obstet Gynaecol Res 35 : 609─622, 2009
15) Langrish CL, Chen Y, Blumenschein WM, et al : IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201 : 233─240, 2005
16) Saito S, Nakashima A, Shima T, et al : Th1/Th2/Th17 and regulatory T-cell paradigm in pregnancy. Am J Reprod Immunol 63 : 601─610, 2010
17) Nakashima A, Ito M, Shima T, et al : Accumulation of IL-17-positive cells in decidua of inevitable abortion cases. Am J Reprod Immunol 64 : 4─11, 2010
18) Wang WJ, Hao CF, Yi-Lin Y, et al : Increased prevalence of T helper 17(Th17)cells in peripheral blood and decidua in unexplained recurrent spontaneous abortion patients. J Reprod Immunol 84 : 164─170, 2010
19) Ochs HD, Ziegler SF, Torgerson TR : FOXP3 acts as a rheostat of the immune response. Immunol Rev 203 : 156─164, 2005
20) Romagnani C, Della Chiesa M, Kohler S, et al : Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+T helper cells and CD4+CD25hi T regulatory cells. Eur J Immunol 35 : 2452─2458, 2005
21) Okamoto M, Oshikawa T, Tano T, et al : Mechanism of anticancer host response induced by OK-432, a streptococcal preparation, mediated by phagocytosis and Toll-like receptor 4 signaling. J Immunother 29 : 78─86, 2006
22) Friebe A, Douglas AJ, Solano E, et al : Neutralization of LPS or blockage of TLR4 signaling prevents stress─triggered fetal loss in murine pregnancy. J Mol Med(Berl) 89 : 689─699, 2011
23) Ober C, Karrison T, Odem RR, et al : Mononuclear-cell immunisation in prevention of recurrent misacarriages : a randomised trial. Lancet 354 : 365─369, 1999
24) T Flint Porter1, LaCoursiere Y, Scott JR : Immunotherapy for recurrent miscarriage. Cochrane Database of Systematic Reviews, Issue4, 2010
25) 竹下俊行 : クリニカルUpdate─臨床最前線,いま何が問題か2.不育症をどう扱う1) 免疫療法の有効性と限界.日産婦誌54 : N─409─N─415,2002
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