臨床婦人科産科66巻7号

2012年06月発行

今月の臨床 卵子の加齢─避けては通れないARTの課題

加齢対策基礎研究

1．卵子のマニピュレーション

著者： 薮内晶子¹ 青野文仁¹ 加藤恵一¹ 竹原祐志¹ 加藤修¹

所属機関： ¹加藤レディスクリニック

ページ範囲：P.558 - P.564

文献概要

●卵細胞質置換法とは，加齢患者由来の卵細胞質を若年ドナー由来の卵細胞質に置換する手法である．

●加齢による卵細胞質の機能不全に対する治療法として，卵細胞質置換法の有用性が提唱されている．

●卵細胞質置換法で作出された卵子は，mtDNAヘテロプラスミーとなり，その安全性が懸念されている．

参考文献

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