臨床婦人科産科67巻8号

2013年08月発行

今月の臨床 婦人科がんの予防戦略と早期診断

子宮体がん

4．家族性子宮体がんと遺伝子異常

著者： 梅根紀代子¹ 阪埜浩司¹ 木須伊織¹ 増田健太¹ 進伸幸¹ 青木大輔¹

所属機関： ¹慶應義塾大学医学部産婦人科学教室

ページ範囲：P.818 - P.824

文献概要

●子宮体がんの一部は遺伝性に発症し，そのリスクが高い症候群や発がんに関与する責任遺伝子が知られている．

●遺伝リスクを適切に評価し，遺伝性素因が疑われる症例には，遺伝子解析も考慮すべきである．

●遺伝性子宮体がんの責任遺伝子や発がん機構の解明は，子宮体がんの発症予防や早期発見に貢献することが期待される．

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