文献詳細
文献概要
合併増大号 今月の臨床 生殖医療の進歩と課題─安全性の検証から革新的知見まで ARTにおける新技術
5.着床前スクリーニング(PGS)
著者: 久具宏司1
所属機関: 1東邦大学医療センター大橋病院産婦人科
ページ範囲:P.34 - P.41
文献購入ページに移動●わが国では,日本産科婦人科学会の見解により,現在PGSを行うことは認められていない.
●FISH法でPGSを行っても,生児獲得率の上昇にはつながらない.array CGH法についてはRCTが進行中である.
●遺伝情報を包括的にスクリーニングすることにより,児の遺伝性疾患だけでなく,一般的な健康状態や健康と関係のない個人の特徴まで,胚移植時の選択の対象となりうる.
●FISH法でPGSを行っても,生児獲得率の上昇にはつながらない.array CGH法についてはRCTが進行中である.
●遺伝情報を包括的にスクリーニングすることにより,児の遺伝性疾患だけでなく,一般的な健康状態や健康と関係のない個人の特徴まで,胚移植時の選択の対象となりうる.
参考文献
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