臨床婦人科産科68巻3号

2014年04月発行

今月の臨床 メタボとロコモ―これからの女性医療のキーワード

女性のロコモティブ症候群 2．骨粗鬆症

5）骨粗鬆症とメタボ関連疾患との連関

著者： 岡崎亮¹

所属機関： ¹帝京大学ちば総合医療センター第三内科

ページ範囲：P.356 - P.362

文献概要

●メタボ一般と骨粗鬆症の関連は明確でない．メタボ構成疾患のうち，高血圧や脂質異常症と骨粗鬆症の関連は少ない．しかし，2型糖尿病は，確立した骨折リスクである．

●2型糖尿病では，骨密度が高くとも骨折する．その原因として，骨基質への最終糖化産物の蓄積や皮質骨多孔性の増大など，骨質の劣化が想定されている．

●メタボの結果，動脈硬化が進展すると，骨折リスクも増大する．

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