臨床婦人科産科68巻3号

2014年04月発行

今月の臨床 メタボとロコモ―これからの女性医療のキーワード

女性のロコモティブ症候群

3．変形性膝関節症

著者： 川口浩¹

所属機関： ¹東京大学医学部整形外科

ページ範囲：P.363 - P.370

文献概要

●変形性膝関節症（膝OA）は，長年の荷重負荷が原因で膝関節軟骨の変性・破壊，関節周囲への骨棘形成を病態とする．

●膝OAの根本的治療法は確立されておらず，国内外の治療ガイドラインにも温度差がある．

●軟骨内骨化シグナルが膝OAの発症メカニズムであることが指摘されつつある．

参考文献

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