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雑誌文献

臨床婦人科産科70巻4号

2016年04月発行

文献概要

増刊号 ─知りたい最新情報がすぐわかる!─不妊・不育症診療パーフェクトガイド 2.不妊症の検査・診断 《女性因子》

卵巣予備能の評価法

著者: 岩瀬明1 滝川幸子2

所属機関: 1名古屋大学医学部附属病院総合周産期母子医療センター 2名古屋大学医学部附属病院産婦人科

ページ範囲:P.56 - P.61

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◉卵巣予備能とは卵巣における卵の量と質を反映し,女性の生殖機能を規定する要因の1つである.卵巣予備能の評価法はovarian reserve test(ORT)と呼ばれる.
◉ORTのうち抗ミュラー管ホルモン(AMH),胞状卵胞数(AFC)は,卵巣の反応性予測における有用性が高い.妊娠・生産の予測因子として満足できるORTはいまだ確立されていない.
◉AMHは,抗がん剤治療やチョコレート囊胞手術の卵巣予備能への影響評価,多囊胞性卵巣症候群の補助診断などにも有用であることが報告されている.

参考文献

1)Broekmans FJ, et al : A systematic review of tests predicting ovarian reserve and IVF outcome. Hum Reprod Update 12 : 685─718, 2006
2)Iwase A, et al : Anti-Müllerian hormone as a marker of ovarian reserve : what have we learned, and what should we know? Reprod Med Biol, 2015(in press)
3)Broer SL, et al : Added value of ovarian reserve testing on patient characteristics in the prediction of ovarian response and ongoing pregnancy : an individual patient data approach. Hum Reprod Update 19 : 26─36, 2013
4)La Marca A, et al : Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers : from theory to practice. Hum Reprod Update 20 : 124─140, 2014
5)Tal R, et al : Antimullerian hormone as predictor of implantation and clinical pregnancy after assisted conception : a systematic review and meta-analysis. Fertil Steril 103 : 119─130. e3, 2015
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7)Kato N, et al : Anti-Mullerian hormone as a possible predictor of fecundability in subfertile women over 38 years : a retrospective cohort study. Gynecol Endocrinol 31 : 22─25, 2015
8)Steiner AZ, et al : Antimullerian hormone as a predictor of natural fecundability in women aged 30-42 years. Obstet Gynecol 117 : 798─804, 2011
9)Hagen CP, et al : Low concentration of circulating antimullerian hormone is not predictive of reduced fecundability in young healthy women : a prospective cohort study. Fertil Steril 98 : 1602─1608. e2, 2012
10)Dolleman M, et al : The relationship between anti-Mullerian hormone in women receiving fertility assessments and age at menopause in subfertile women : evidence from large population studies. J Clin Endocrinol Metab 98 : 1946─1953, 2013
11)Dolleman M, et al : Anti-Müllerian hormone is a more accurate predictor of individual time to menopause than mother's age at menopause. Hum Reprod 29 : 584─591, 2014
12)Iliodromiti S, et al : Can anti-Müllerian hormone predict the diagnosis of polycystic ovary syndrome? a systematic review and meta-analysis of extracted data. J Clin Endocrinol Metab 98 : 3332─3340, 2013
13)Iwase A, et al : Anti-Müllerian hormone and assessment of ovarian reserve after ovarian toxic treatment : a systematic narrative review. Reprod Sci 22 : 519─526, 2015
14)Wallace WH, et al : Fertility preservation for girls and young women with cancer : population-based validation of criteria for ovarian tissue cryopreservation. Lancet Oncol 15 : 1129─1136, 2014
15)Raffi F, et al : The impact of excision of ovarian endometrioma on ovarian reserve : a systematic review and meta-analysis. J Clin Endocrinol Metab 97 : 3146─3154, 2012
16)Iwase A, et al : Anti-Müllerian hormone levels after laparoscopic cystectomy for endometriomas as a possible predictor for pregnancy in infertility treatments. Gynecol Endocrinol, 2015[Epub ahead of print]
17)Iwase A, et al : Usefulness of the ultrasensitive anti-Müllerian hormone assay for predicting true ovarian reserve. Reprod Sci, 2015[Epub ahead of print]

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1294

印刷版ISSN:0386-9865

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