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臨床婦人科産科70巻4号

2016年04月発行

文献概要

増刊号 ─知りたい最新情報がすぐわかる!─不妊・不育症診療パーフェクトガイド 8.不育症の検査・診断

内分泌代謝異常による不育症の診断法

著者: 和泉俊一郎1 高橋千果1 篠田真理1

所属機関: 1東海大学医学部産婦人科・遺伝診療科

ページ範囲:P.339 - P.342

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◉まずは基礎体温測定と高温期黄体ホルモン検査を行い,下垂体機能(プロラクチン,LH,FSH,TRH負荷テスト),および甲状腺機能(freeT3,freeT4,TSH)と抗甲状腺ペルオキシダーゼ抗体の検査も行う.
◉糖尿病検査(空腹時血糖,HbA1c,糖負荷テスト)と卵巣予備能は追加項目である.

参考文献

1)齋藤 滋 : 不育症治療に関する再評価と新たなる治療法の開発に関する研究総括.平成20─22年度厚生労働科学研究費補助金(生育疾患克服等次世代育成基盤研究事業).p1,2011
2) Ford HB, et al : Recurrent pregnancy loss : etiology, diagnosis, and therapy. Rev Obstet Gynecol 2 : 76─83, 2009
3)Christiansen OB, et al : Evidence-based investigations and treatments of recurrent pregnancy loss. Fertil Steril 83 : 821─839, 2005
4)Krassas GE, et al : Thyroid function and human reproductive health. Endocr Rev 31 : 702─755, 2010
5)Anselmo J, et al : Fetal loss associated with excess thyroid hormone exposure. JAMA 292 : 691─695, 2004
6)Negro R, et al : Increased pregnancy loss rate in thyroid antibody negative women with TSH levels between 2.5 and 5.0 in the first trimester of pregnancy. J Clin Endocrinol Metab 95 : E44─48, 2010
7)Chen L, et al : Thyroid autoimmunity and miscarriage : a meta-analysis. Clin Endocrinol(Oxf) 74 : 513─519, 2011
8)Thangaratinam S, et al : Association between thyroid autoantibodies and miscarriage and preterm birth : meta-analysis of evidence. BMJ 342 : d2616, 2011
9)Balasch J, et al : The usefulness of endometrial biopsy for luteal phase evaluation in infertility. Hum Reprod 7 : 973─977, 1992
10)Ogasawara M, et al : Are serum progesterone levels predictive of recurrent miscarriage in future pregnancies? Fertil Steril 68 : 806─809, 1997
11)Goldstein P, et al : A meta-analysis of randomized control trials of progestational agents in pregnancy. Br J Obstet Gynaecol 96 : 265─274, 1989
12)Hirahara F, et al : Hyperprolactinemic recurrent miscarriage and results of randomized bromocriptine treatment trials. Fertil Steril 70 : 246─252, 1998
13)Greene MF, et al : First-trimester hemoglobin A1 and risk for major malformation and spontaneous abortion in diabetic pregnancy. Teratology 39 : 225─231, 1989
14)Miller E, et al : Elevated maternal hemoglobin A1c in early pregnancy and major congenital anomalies in infants of diabetic mothers. N Engl J Med 304 : 1331─1334, 1981
15)Ylinen K, et al : Risk of minor and major fetal malformations in diabetics with high haemoglobin A1c values in early pregnancy. Br Med J(Clin Res Ed) 289 : 345─346, 1984
16)Mills JL, et al : Incidence of spontaneous abortion among normal women and insulin-dependent diabetic women whose pregnancies were identified within 21 days of conception. N Engl J Med 319 : 1617─1623, 1988
17)Glueck CJ, et al : Pregnancy outcomes among women with polycystic ovary syndrome treated with metformin. Hum Reprod 17 : 2858, 2002
18)Rai R, et al : Polycystic ovaries and recurrent miscarriage : a reappraisal. Hum Reprod 15 : 612─615, 2000
19)Okon MA, et al : Serum androgen levels in women who have recurrent miscarriages and their correlation with markers of endometrial function. Fertil Steril 69 : 682─690, 1998
20)Bonney RC, et al : The endocrinology of implantation and early pregnancy. Baillieres Clin Endocrinol Metab 4 : 207─231, 1990
21)Craig LB, et al : Increased prevalence of insulin resistance in women with a history of recurrent pregnancy loss. Fertil Steril 78 : 487─490, 2002
22)Glueck CJ, et al : Continuing metformin throughout pregnancy in women with polycystic ovary syndrome appears to safely reduce first-trimester spontaneous abortion : a pilot study. Fertil Steril 75 : 46─52, 2001
23)Jakubowicz DJ, et al : Effects of metformin on early pregnancy loss in the polycystic ovary syndrome. J Clin Endocrinol Metab 87 : 524─529, 2002
24)Palomba S, et al : Clomiphene citrate versus metformin as first-line approach for the treatment of anovulation in infertile patients with polycystic ovary syndrome. J Clin Endocrinol Metab 92 : 3498─3503, 2007
25)Legro RS, et al : Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome. N Engl J Med 356 : 551─566, 2007
26)Trout SW, et al : Do women with unexplained recurrent pregnancy loss have higher day 3 serum FSH and estradiol values? Fertil Steril 74 : 335─337, 2000

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1294

印刷版ISSN:0386-9865

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