臨床婦人科産科70巻9号

2016年09月発行

今月の臨床 卵管は脇役か？─その生理と病態

卵管の病理

卵管癌─発癌機構と取り扱い

著者： 本原剛志¹ 片渕秀隆¹

所属機関： ¹熊本大学大学院生命科学研究部産科婦人科学

ページ範囲：P.848 - P.854

文献概要

●BRCA遺伝子変異を有する女性に対するrisk-reducing salpingo-oophorectomy（RRSO）によって摘出された卵巣および卵管の詳細な病理学的解析の結果，骨盤腔内に進展するhigh-grade漿液性腺癌が卵管上皮を起源としている可能性が示された．

●骨盤腔内に生じるhigh-grade漿液性癌の発癌機構の解明のためには，卵管采を含めた卵管の全長にわたる網羅的な病理組織学的検討が重要である．

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