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臨床婦人科産科71巻1号

2017年01月発行

文献概要

合併増大号 今月の臨床 性ステロイドホルモン研究の最前線と臨床応用 臨床各論 : 使い方の実際

FLUTS

著者: 樋口毅1

所属機関: 1弘前大学大学院保健学研究科看護学領域

ページ範囲:P.104 - P.109

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●女性下部尿路症状(FLUTS)でのエストロゲン治療では局所(腟内)投与が第一選択となる.

●外陰腟萎縮(VVA)からFLUTSが起こることもある.エストロゲンを使ったときにはFLUTSへの効果も評価する.

●全身投与のエストロゲンでは,尿失禁の予防効果,症状軽減効果ともに期待できない.

参考文献

1)Iosif CS, et al : Estrogen receptors in the human female lower urinary tract. Am J Obstet Gynecol 141 : 817─820, 1981
2)Portman DJ, et al : Genitourinary syndrome of menopause : new terminology for vulvovaginal atrophy from the International Society for the Study of Women's Sexual Health and the North American Menopause Society. Menopause 21 : 1063─1068, 2014
3)Rahn DD, et al : Vaginal estrogen for genitourinary syndrome of menopause : A systematic review. Obstet Gynecol 124 : 1147─1156, 2014
4)Brown JS, et al : Urinary tract infections in postmenopausal women : Effect of hormone therapy and risk factors. Obstet Gynecol 98 : 1045─1052, 2001
5)Simunic V, et al : Local estrogen treatment in patients with urogenital symptoms. Int J Gynaecol Obstet 82 : 187─197, 2003
6)Le Ray I, et al : Local estrogen therapy and risk of breast cancer recurrence among hormone-treated patients : A nested case-control study. Breast Cancer Res Treat 135 : 603─609, 2012
7)O'Meara ES, et al : Hormone replacement therapy after a diagnosis of breast cancer in relation to recurrence and mortality. J Natl Cancer Inst 93 : 754─762, 2001
8)Cardozo L, et al : A systematic review of the effects of estrogens for symptoms suggestive of overactive bladder. Acta Obstet Gynecol Scand 83 : 892─897, 2004
9)Tseng LH, et al : Randomized comparison of tolterodine with vaginal estrogen cream versus tolterodine alone for the treatment of postmenopausal women with overactive bladder syndrome. Neurourology and Urodynamics 28 : 47─51, 2009
10)Ismail SI,et al : Oestrogens for treatment or prevention of pelvic organ prolapse in postmenopausal women. Cochrane Database Syst Rev : CD007063, 2010
11)Trutnovsky G, et al : Pelvic floor dysfunction-does menopause duration matter? Maturitas 76 : 134─138, 2013
12)Ishiko O, et al : Hormone replacement therapy plus pelvic floor muscle exercise for postmenopausal stress incontinence. A randomized, controlled trial. J Reprod Med 46 : 213─220, 2001
13)Felding C, et al : Preoperative treatment with oestradiol in women scheduled for vaginal operation for genital prolapse. A randomised, double-blind trial. Maturitas 15 : 241─249, 1992
14)Hirai K, et al : Estrogen and urinary incontinence. Int J Urol 16 : 45─48, 2009
15)Cody JD, et al : Oestrogen therapy for urinary incontinence in post-menopausal women. Cochrane Database Syst Rev 10 : CD001405, 2012
16)Edwall L, et al : Different estrogen sensitivity of urogenital tissue from women with and without stress urinary incontinence. Neurourol Urodyn 28 : 516─520, 2009
17)Robinson D, et al : Oestrogens and overactive bladder. Neurourol Urodyn 33 : 1086─1094, 2014

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1294

印刷版ISSN:0386-9865

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