臨床婦人科産科72巻12号

2018年12月発行

今月の臨床 女性のアンチエイジング─老化のメカニズムから予防・対処法まで

部位別 : 老化のメカニズムと予防・対処法

骨の老化

著者： 太田邦明¹ 高橋俊文¹ 水沼英樹¹

所属機関： ¹福島県立医科大学ふくしま子ども・女性医療支援センター

ページ範囲：P.1214 - P.1219

文献概要

●近年，骨芽細胞と破骨細胞の細胞老化現象が解明されつつある．

●骨の老化機構は，骨芽細胞数・分化を低下させ，破骨細胞数・分化を増加させることで，骨芽細胞・破骨細胞バランスが不均衡になる現象である．

●抗老化マーカーをターゲットとした治療法の開発が期待される．

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