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雑誌文献

臨床婦人科産科73巻6号

2019年06月発行

文献概要

今月の臨床 多胎管理のここがポイント―TTTSとその周辺 TTTS

診断基準とリスク因子

著者: 村越毅1

所属機関: 1聖隷浜松病院産婦人科・総合周産期母子医療センター

ページ範囲:P.518 - P.526

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●1絨毛膜2羊膜双胎において,吻合血管に起因する特徴的な病態(双胎間輸血症候群,一児発育不全,一児死亡による急性胎児間輸血,双胎貧血多血症など)を理解する.

●両児間のアンバランスに注目し管理する.特に①羊水量の不均衡,②発育の不均衡,③ヘモグロビン濃度の不均衡などの症状に注目することが大切である.

●双胎間輸血症候群に対する胎児鏡下胎盤吻合血管レーザー凝固術など,病態によっては胎児期の治療が可能で予後が改善する疾患が存在する.

参考文献

1)Mahieu-Caputo D, et al : Paradoxic activation of the renin-angiotensin system in twin-twin transfusion syndrome : an explanation for cardiovascular disturbances in the recipient. Pediatr Res 58 : 685-688, 2005
2)Slaghekke F, et al : Twin anemia-polycythemia sequence : diagnostic criteria, classification, perinatal management and outcome. Fetal Diagn Ther 27 : 181-190, 2010
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13)Nakayama S, et al : Perinatal complications of monochorionic diamniotic twin gestations with discordant crown-rump length determined at mid-first trimester. J Obstet Gynaecol Res 40 : 418-423, 2014
14)Lewi L, et al : The role of ultrasound examination in the first trimester and at 16 weeks' gestation to predict fetal complications in monochorionic diamniotic twin pregnancies. Am J Obstet Gynecol 199 : 493. e1-e7, 2008
15)Sebire NJ, et al : Inter-twin membrane folding in monochorionic pregnancies. Ultrasound Obstet Gynecol 11 : 324-327, 1998
16)Sebire NJ, et al : Early prediction of severe twin-to-twin transfusion syndrome. Hum Reprod 15 : 2008-2010, 2000
17)Yamamoto R, et al : The use of amniotic fluid discordance in the early second trimester to predict severe twin-twin transfusion syndrome. Fetal Diagn Ther 34 : 8-12, 2013
18)Sebire NJ, et al : Increased nuchal translucency thickness at 10-14 weeks of gestation as a predictor of severe twin-to-twin transfusion syndrome. Ultrasound Obstet Gynecol 10 : 86-89, 1997
19)Matias A, et al : Search for hemodynamic compromise at 11-14 weeks in monochorionic twin pregnancy : is abnormal flow in the ductus venosus predictive of twin-twin transfusion syndrome? J Matern Fetal Neonatal Med 18 : 79-86, 2005

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1294

印刷版ISSN:0386-9865

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