臨床婦人科産科74巻10号

2020年10月発行

今月の臨床 胎盤・臍帯・羊水異常の徹底理解―病態から診断・治療まで

TOPICS

臍帯血幹細胞による細胞療法・再生医療

著者： 上田一仁¹ 佐藤義朗¹ 早川昌弘¹

所属機関： ¹名古屋大学医学部附属病院総合周産期母子医療センター

ページ範囲：P.1062 - P.1067

文献概要

●臍帯血幹細胞には，造血幹細胞や造血前駆細胞だけでなく，間葉系幹細胞（MSC）をはじめとする他の幹細胞も含まれている．

●臍帯血幹細胞は，神経系細胞への分化能，神経修復作用，血管新生作用，抗炎症作用など多岐にわたる作用を通じて治療効果を発揮する．

●日本ではHIEに対する自己臍帯血幹細胞療法の臨床試験が2015年から開始され，第1相試験で安全性が確認された．まもなく（2020年7月現在）第2相試験が開始される予定である．

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