臨床婦人科産科74巻9号

2020年09月発行

今月の臨床 産婦人科医に最低限必要な正期産新生児管理の最新知識（Ⅱ）―母体合併症の影響は？　新生児スクリーニングはどうする？ 母体合併症

ヘルペス合併妊婦から出生した児の取り扱い

著者： 吉田美智子¹ 宮入烈¹

所属機関： ¹国立成育医療研究センター感染防御対策室

ページ範囲：P.885 - P.890

●新生児ヘルペス感染症は死亡率が高く，救命できても後遺症を残す予後不良の疾患である．

●性器ヘルペス合併妊婦から分娩時に感染するとされるが，母体は無症状の場合が多い．

●新生児ヘルペス感染症を疑ったら，確定診断を待たずに治療を開始する．

参考文献

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2）James SH, et al : Neonatal herpes simplex virus infection : epidemiology and treatment. Clin Perinatol 42 : 47-59, viii, 2015

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9）David W, et al, for the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group : Oral acyclovir suppression and neurodevelopment after neonatal herpes. N Engl J Med 365 : 1284-1292, 2011

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11）Tunkel AR, et al : The management of encephalitis : clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis 47 : 303-327, 2008

12）Britton PN, et al : Consensus guidelines for the investigation and management of encephalitis in adults and children in Australia and New Zealand. Intern Med J 45 : 563-576, 2015

13）Kneen R, et al : Management of suspected viral encephalitis in children-Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group national guidelines. J Infect 64 : 449-477, 2012

14）「単純ヘルペス脳炎診療ガイドライン」作成委員会 : 単純ヘルペス脳炎診療ガイドライン2017．南江堂，2017

15）Britton PN, et al : Consensus guidelines for the investigation and management of encephalitis in adults and children in Australia and New Zealand. Intern Med J 45 : 563-576, 2015

16）Kneen R, et al : Management of suspected viral encephalitis in children-Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group national guidelines. J Infect 64 : 449-477, 2012

17）「単純ヘルペス脳炎診療ガイドライン」作成委員会 : 単純ヘルペス脳炎診療ガイドライン2017，南江堂，2017