臨床婦人科産科75巻1号

2021年01月発行

合併増大号　今月の臨床 生殖医療の基礎知識アップデート―患者説明に役立つ最新エビデンス・最新データ 不育症の検査・治療

不育症に対する血液凝固系検査―プロテインS欠乏症と第Ⅻ因子欠乏症について

著者： 藤田太輔¹ 大道正英¹

所属機関： ¹大阪医科大学産婦人科学教室

ページ範囲：P.150 - P.158

●プロテインSと第Ⅻ因子は不育症との関連性について不明な点が多く，不育症に対する血液凝固系検査として推奨されていない．

●プロテインS欠乏症合併妊娠と第Ⅻ因子欠乏症合併妊娠において，不育症の治療目的にアスピリンやヘパリンを投与すべきかどうかについては，確固たるエビデンスがない．

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