臨床婦人科産科75巻2号

2021年03月発行

今月の臨床 妊娠・分娩時の薬物治療―最新の使い方は？　留意点は？

抗悪性腫瘍薬―妊婦への投与が禁忌の医薬品と妊娠期ごとの副作用

著者： 小畠真奈¹

所属機関： ¹筑波大学医学医療系総合周産期医学

ページ範囲：P.268 - P.277

文献概要

●サリドマイド，タモキシフェン，メトトレキサート，ブスルファン，トラスツズマブ，ベバシズマブ，三酸化二ヒ素は妊娠中に使用すべきではない．

●妊娠継続を希望する場合，妊娠第1三半期には抗悪性腫瘍薬を使用すべきではない．

●妊娠第2三半期以降は，抗悪性腫瘍薬（添付文書上「禁忌」とされるものを含む）による治療を行うことがある．

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