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雑誌文献

臨床婦人科産科76巻8号

2022年08月発行

文献概要

今月の臨床 HPVワクチン勧奨再開―いま知りたいことのすべて 検診との関係

ワクチン接種を前提とした子宮頸がん検診の将来像

著者: 藤井多久磨1

所属機関: 1藤田医科大学医学部産婦人科学

ページ範囲:P.800 - P.806

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●子宮頸がん検診では,HPV検査のほうが細胞診より感度がよいが特異度が劣る.

●細胞診陰性だがHPV陽性例の前がん病変進展のリスクが注目を集めている.

●HPVワクチンと検診で子宮頸がん予防の相乗効果が期待できる.

●HPV単独検査陽性例のトリアージでは細胞診が活用されているが,細胞診免疫染色法も期待される手法の1つである.

参考文献

1)国立がん研究センター「健診ガイドライン作成と科学的根拠基づくがん検診推進のための研究」班 : 有効性評価に基づく子宮頸がん検診ガイドライン2019年度版.国立がん研究センター社会と健康研究センター,2020
2)Ronco G, et al : Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical intraepithelial neoplasia : a randomised controlled trial. Lancet Oncol 11 : 249-57, 2010
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19)Perkins RB, et al : 2019 ASCCP risk-based management consensus guidelines for abnormal cervical cancer screening tests and cancer precursors. J Low Genit Tract Dis 24 : 102-131, 2020
20)Hall MT, et al : Projected future impact of HPV vaccination and primary HPV screening on cervical cancer rates from 2017-2035 : example from Australia. PLoS One 13 : e0185332, 2018
21)藤井多久磨,他 : 【子宮頸がん予防―日本はどうする?―】HPVワクチン接種プログラムは子宮頸がん検診をどのように変えるのか? 産婦の実際69 : 275-283, 2020
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掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1294

印刷版ISSN:0386-9865

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