臨床婦人科産科77巻3号

2023年04月発行

今月の臨床 乳腺―産婦人科医が知っておくべき必須知識

乳がんと妊孕性温存，妊娠出産，再建

乳がんと妊孕性温存

著者： 中村健太郎¹ 洞下由記¹ 鈴木直¹

所属機関： ¹聖マリアンナ医科大学産婦人科学

ページ範囲：P.389 - P.396

文献概要

●乳がん治療は妊孕性低下リスクがあるため，若年乳がん患者には妊孕性温存に関する情報を初回のがん治療前に提供すべきである．

●妊孕性温存療法は，がん治療に支障のない範囲内で行うべきであり，個々の患者の希望や乳がんの状況を考慮して選択される．

●胚凍結，卵子凍結は確立された方法であるが，治療開始前の凍結個数には限界があり，妊娠率は凍結時の年齢に依存する．

●卵巣組織凍結の主なる適応は35歳以下であり，移植による卵巣機能回復が期待できる方法だが，有効性と安全性の検証は十分でない．

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