臨床婦人科産科77巻7号

2023年07月発行

今月の臨床 細菌叢から読み解く女性と子どものヘルスケア

小児

腸内細菌叢と小児の自閉スペクトラム症

著者： 金子一成¹

所属機関： ¹関西医科大学医学部小児科学講座

ページ範囲：P.718 - P.725

文献概要

●ヒトの常在菌の90％以上を占める消化管の細菌集団は腸内細菌叢と呼ばれ，遺伝子解析による微生物同定技術の進歩によってヒトの健康における役割が解明されつつある．

●腸内細菌叢の形成期である，受胎から1,000日間（生後2歳まで）の栄養環境が神経系の発達の鍵となる．

●脳の発達における腸内細菌叢の重要性が認識されるにつれ，自閉スペクトラム症の腸内細菌叢が研究の対象として重要性を増している．

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