臨床検査50巻2号

2006年02月発行

今月の主題 花粉症克服への展望 総説

アレルゲンとしての花粉

著者： 阪口雅弘¹ 藤村孝志¹

所属機関： ¹理化学研究所免疫・アレルギー科学総合研究センターワクチンデザイン研究チーム

ページ範囲：P.129 - P.137

国民の10%以上がスギ花粉症であると推定されている．その主要なアレルゲン蛋白として，Cry j 1，Cry j 2が報告されている．現在，この2つのアレルゲンについて解析が進み，その成果を基に治療用ワクチンの開発も進んでいる．また，サルやイヌにも自然発症のスギ花粉症が存在し，そのアレルゲンに対する反応性はヒトによく似ている．〔臨床検査　50：129-137，2006〕

参考文献

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