文献詳細
文献概要
今月の主題 乳癌と臨床検査 総説
乳癌の治療の選択
著者: 武山浩1
所属機関: 1東京慈恵会医科大学付属第三病院外科
ページ範囲:P.15 - P.22
文献購入ページに移動 現在乳癌は日本では女性の癌のなかで罹患率第一位となっており,社会の関心も高い.癌の治療は手術,放射線治療,化学療法(抗癌剤治療)が基本とされているが乳癌はこれらの治療すべてが有効な疾患とされている.また乳腺組織は卵巣ホルモンが作用する標的臓器であるため,これら治療に加えて卵巣ホルモンを阻害するいわゆる内分泌療法(ホルモン療法)が約60~70%の乳癌において有効である.これらの治療法の選択について診断から治療の流れに沿って概説する.〔臨床検査 51:15-22,2007〕
参考文献
1) Tozaki M, Uno S, Takeyama H, et al:Histologic breast cancer extent after neoadjuvant chemotherapy:comparison with multidetector CT and dynamic MRI. Radiation Medicine 22:246-253, 2004
2) Fisher B, Anderson S, Bryant J, et al:Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 347:1233-1241, 2002
3) Krag D, Weaver D, Ashikaga T, et al:The sentinel node in breast cancer―a multicenter validation study. N Engl J Med 339:941-946, 1998
4) Overgaard M, Christensen JJ, Johansen H, et al:Postmastectomy irradiation in high-risk breast cancer patients. Present status of the Danish Breast Cancer Cooperative Group trials. Acta Oncol 27:707-714, 1988
5) Ragaz J, Jackson SM, Le N, et al:Adjuvant radiotherapy and chemotherapy in node-positive premenopausal women with breast cancer. N Engl J Med 337:956-962, 1997
6) Ratanatharathorn V, Powers WE, Moss WT, et al:Bone metastasis:review and critical analysis of random allocation trials of local field treatment. Int J Radiat Oncol Biol Phys 44:1-18, 1999
7) Early Breast Cancer Trialists’ Collaborative Group:Tamoxifen for early breast cancer:an overview of the randomised trials. Lancet 351:1451-1467, 1998
8) Klijn JG, Blamey RW, Boccardo F, et al:Combined tamoxifen and luteinizing hormone-releasing hormone(LHRH)agonist versus LHRH agonist alone in premenopausal advanced breast cancer:a meta-analysis of four randomized trials. J Clin Oncol 19:343-353, 2001
9) Bonneterre J, Buzdar A, Nabholtz JM, et al:Arimidex Writing Committee;Investigators Committee Members. Anastrozole is superior to tamoxifen as first-line therapy in hormone receptor positive advanced breast carcinoma. Cancer 92:2247-2258, 2001
10) Bear HD, Anderson S, Brown A, et al:National Surgical Adjuvant Breastand Bowel Project Protocol B-27. The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide:preliminary results from National Surgical Adjuvant Breast and Bowel Project Protocol B-27. J Clin Oncol 21:4165-4174, 2003
11) Early Breast Cancer Trialists’ Collaborative Group:Polychemotherapy for early breast cancer:an overview of randomised trials. Lancet 352:930-942, 1998
12) Sparano JA, Neuberg D, Glick JH, et al:Phase Ⅱ trial of biweekly paclitaxel and cisplatin in advanced breast carcinoma:an Eastern Cooperative Oncology Group study. J Clin Oncol 15:1880-1884, 1997
13) Cobleigh MA, Vogel CL, Tripathy D, et al:Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 17:2639-2648, 1999
掲載誌情報