臨床検査53巻9号

2009年09月発行

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今月の主題 脳磁図で何がわかるか？ 各論

小児てんかんの磁場源解析

著者： 藤原久子¹ 大坪宏²

所属機関： ¹シンシナティ小児病院神経科 ²トロント小児病院神経科臨床神経生理部門

ページ範囲：P.1057 - P.1064

　小児神経科領域のなかで小児てんかんの占める割合は大きい．脳磁図(MEG)は，てんかん棘波の電流源の双極子推定を行うことで，小児てんかんの診断・治療において重要な役割を占めるようになってきている．小児に特異的なてんかんとてんかん症候群では，てんかん棘波の局在部位と性質をMEGで評価できる．小児難治性てんかんの多くが側頭葉外てんかんであり，神経移動障害の病理所見を示すが，このような症例においても，MEGはてんかん焦点を正確に同定でき，難治性てんかんに対する外科的治療におおいに役立っている．小児の発達・学習障害などにもMEGによる脳機能障害の解明を行う研究がなされている．本稿では，小児に特異的な良性てんかんの診断，難治性てんかんの外科的治療の術前検査，発達・学習障害へのMEGの応用について述べる．

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