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雑誌文献

臨床検査55巻10号

2011年10月発行

文献概要

今月の主題 カルシウム・リン・ビタミンDの再評価 各論 〈病態生理と検査〉

副甲状腺機能障害

著者: 田中弘之1

所属機関: 1岡山済生会総合病院小児科

ページ範囲:P.987 - P.992

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副甲状腺機能異常の中で機能低下症について,その原因と病態,病態生理からみた治療管理の概略を述べた.副甲状腺機能低下症は様々な原因で発症し,その鑑別は治療方針の決定に重要である.また,治療においては欠落ホルモンを補充することは難しく低Ca血症を活性型ビタミンDの投与で補正しているだけであるため,高Ca尿症の発症に注意する必要がある.

参考文献

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2) Nagamine K, Peterson P, Scott HS, et al : Positional cloning of the APECED gene. Nat Genet 17:393-398,1997
3) Alimohammadi M, Björklund P, Hallgren A, et al : Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen. N Engl J Med 358:1018-1028,2008
4) Sunthornthepvarakul T, Churesigaew S, Ngowngarmratana S : A novel mutation of the signal peptide of the preproparathyroid hormone gene associated with autosomal recessive familial isolated hypoparathyroidism. J Clin Endocrinol Metab 84:3792-3796,1999
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8) Nakamura Y, Matsumoto T, Tamakoshi A, et al : Prevalence of idiopathic hypoparathyroidism and pseudohypoparathyroidism in Japan. J Epidemiol 10:29-33,2000
9) Winer KK, Yanovski JA, Cutler GB Jr : Synthetic human parathyroid hormone 1-34 vs calcitriol and calcium in the treatment of hypoparathyroidism. JAMA 276:631-636,1996
10) Winer KK, Yanovski JA, Sarani B, et al : A randomized, cross-over trial of once-daily versus twice-daily parathyroid hormone 1-34 in treatment of hypoparathyroidism. J Clin Endocrinol Metab 83:3480-3486,1998
11) Winer KK, Ko CW, Reynolds JC, et al : Long-term treatment of hypoparathyroidism : a randomized controlled study comparing parathyroid hormone-(1-34) versus calcitriol and calcium. J Clin Endocrinol Metab 88:4214-4220,2003
12) Arlt W, Fremerey C, Callies F, et al : Well-being, mood and calcium homeostasis in patients with hypoparathyroidism receiving standard treatment with calcium and vitamin D. Eur J Endocrinol 146:215-222,2002

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1367

印刷版ISSN:0485-1420

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