臨床検査56巻13号

2012年12月発行

今月の主題 アルコール依存症 話題

アルコールと発癌

著者： 横山顕¹

所属機関： ¹国立病院機構久里浜医療センター臨床研究部

ページ範囲：P.1467 - P.1471

1．はじめに

　2009年までにWHO(World Health Organization)のIARC(International Agency for Research on Cancer)は，飲酒が原因で発癌する臓器は口腔，咽頭，喉頭，食道，肝臓，結腸・直腸と女性の乳房であり，アルコール飲料，飲料中のエタノール，飲酒と関連して発生するアセトアルデヒドの3つを，発癌物質と結論づけた(表)¹⁾．2005年の厚生労働省多目的コホート研究(Japan Public Health Center-based prospective Study；JPHC Study)は，飲酒関連癌のリスクは1日1合未満相当(以下日本酒換算，ビール500mlに相当)の習慣飲酒者では，ときどき飲酒する人の2.3倍であり，男性の癌死亡の13％が1日2合の飲酒に起因すると概算した²⁾．

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