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雑誌文献

臨床検査57巻7号

2013年07月発行

文献概要

今月の特集2 感染症と発癌

HTLV-1と成人T細胞白血病

著者: 田邉順子1 松岡雅雄1

所属機関: 1京都大学ウイルス研究所ヒトレトロウイルス研究施設

ページ範囲:P.768 - P.775

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■ヒトT細胞白血病ウイルス1型(HTLV-1)の感染には生きた感染細胞が必須であるため,生体内で感染細胞の増殖を促進する.

■成人T細胞白血病(ATL)の確定診断にはHTLV-1のモノクローナルな組み込みを証明することが必要である.

参考文献

1)Matsuoka M, Jeang KT:Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation. Nat Rev Cancer 7:270-280,2007
2)Watanabe T:Current status of HTLV-1 infection. Int J Hematol 94:430-434,2011
3)Derse D, Hill SA, Lloyd PA, et al:Examining human T-lymphotropic virus type 1 infection and replication by cell-free infection with recombinant virus vectors. J Virol 75:8461-8468,2001
4)Igakura T, Stinchcombe JC, Goon PK, et al:Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton. Science 299:1713-1716,2003
5)Pais-Correia AM, Sachse M, Guadagnini S, et al:Biofilm-like extracellular viral assemblies mediate HTLV-1 cell-to-cell transmission at virological synapses. Nat Med 16:83-89,2010
6)Li HC, Biggar RJ, Miley WJ, et al:Provirus load in breast milk and risk of mother-to-child transmission of human T lymphotropic virus type I. J Infect Dis 190:1275-1278,2004
7)Iwanaga M, Watanabe T, Utsunomiya A, et al:Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan. Blood 116:1211-1219,2010
8)Manel N, Kim FJ, Kinet S, et al:The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. Cell 115:449-459,2003
9)Doi K, Wu X, Taniguchi Y, et al:Preferential selection of human T-cell leukemia virus type I provirus integration sites in leukemic versus carrier states. Blood 106:1048-1053,2005
10)Etoh K, Tamiya S, Yamaguchi K, et al:Persistent clonal proliferation of human T-lymphotropic virus type I-infected cells in vivo. Cancer Res 57:4862-4867,1997
11)Gillet NA, Malani N, Melamed A, et al:The host genomic environment of the provirus determines the abundance of HTLV-1-infected T-cell clones. Blood 117:3113-3122,2011
12)Satou Y, Yasunaga J, Yoshida M, et al:HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells. Proc Natl Acad Sci U S A 103:720-725,2006
13)Satou Y, Yasunaga J, Zhao T, et al:HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo. PLoS Pathog 7:e1001274,2011
14)Cook LB, Rowan AG, Melamed A, et al:HTLV-1-infected T cells contain a single integrated provirus in natural infection. Blood 120:3488-3490,2012

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1367

印刷版ISSN:0485-1420

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