臨床検査57巻7号

2013年07月発行

今月の特集2 感染症と発癌

ヒトパピローマウイルスと子宮頸癌

著者： 今野良¹

所属機関： ¹自治医科大学附属さいたま医療センター産婦人科

ページ範囲：P.783 - P.789

■子宮頸癌におけるHPV（human papillomavirus）の発癌メカニズムの役割は，ほぼ解明された．

■子宮頸癌においては，検診におけるHPV検査やHPVワクチンの導入が進みつつあり，予防できる癌として臨床像が大きく変貌している．

■外陰，腟，陰茎，肛門などのいわゆる性器肛門癌においても，HPVの関連性は明らかになった．

■最近，HPV関連頭頸部癌の増加が報告され，特に，中咽頭癌におけるHPVの関与の根拠が次第に大きくなってきている．

■HPV関連中咽頭癌では，非HPV関連中咽頭癌に比して，予後が良い．

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