文献詳細
文献概要
今月の特集2 Antimicrobial stewardship
Antimicrobial stewardshipにおける薬剤師の役割
著者: 前田幹広1
所属機関: 1聖マリアンナ医科大学病院薬剤部
ページ範囲:P.58 - P.62
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●stewardship多職種チームのコアメンバーとして,感染症のトレーニングを受けた臨床薬剤師が必要である.
●薬剤師がかかわるのは“介入とフィードバック”と“フォーミュラリーの作成と抗菌薬使用制限”である.
●感染症専門薬剤師がASPチームで介入をすることによって,抗菌薬の適正使用を推進することが可能となる.
●病棟薬剤師を活用して,わが国独自のASPの構築を目指さなくてはならない.
●stewardship多職種チームのコアメンバーとして,感染症のトレーニングを受けた臨床薬剤師が必要である.
●薬剤師がかかわるのは“介入とフィードバック”と“フォーミュラリーの作成と抗菌薬使用制限”である.
●感染症専門薬剤師がASPチームで介入をすることによって,抗菌薬の適正使用を推進することが可能となる.
●病棟薬剤師を活用して,わが国独自のASPの構築を目指さなくてはならない.
参考文献
1)Dellit TH, Owens RC, McGowan JE Jr, et al:Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 44:159-177,2007
2)Barlam TF, Cosgrove SE, Abbo LM, et al:Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin Infect Dis 62:e51-e77,2016
3)日本病院薬剤師会:平成27年度「病院薬剤部門の現状調査」集計結果報告.日病薬師会誌 7:761-832,2016
4)Drew RH, White R, MacDougall C, et al:Insights from the Society of Infectious Diseases Pharmacists on antimicrobial stewardship guidelines from the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Pharmacotherapy 29:593-607,2009
5)Yu K, Rho J, Morcos M, Nomura J, et al:Evaluation of dedicated infectious diseases pharmacists on antimicrobial stewardship teams. Am J Health Syst Pharm 71:1019-1028,2014
6)Centers for Disease Control and Prevention (CDC):Core Elements of Hospital Antibiotic Stewardship Programs,2014(http://www.cdc.gov/getsmart/healthcare/implementation/core-elements.html)
7)Carling P, Fung T, Killion A, et al:Favorable impact of a multidisciplinary antibiotic management program conducted during 7 years. Infect Control Hosp Epidemiol 24:699-706,2003
8)Tyler LS, Cole SW, May JR, et al:ASHP guidelines on the pharmacy and therapeutics committee and the formulary system. Am J Health Syst Pharm 65:1272-1283,2008
9)U.S. Department of Health and Human Service:FDA Drug Safety Communication: Cefepime and risk of seizure in patients not receiving dosage adjustments for kidney impairment,2012(http://www.fda.gov/Drugs/DrugSafety/ucm309661.htm)
10)Schentag JJ, Gilliland KK, Paladino JA. What have we learned from pharmacokinetic and pharmacodynamic theories? Clin Infect Dis 32(Suppl 1):S39-S46,2001
11)Owens RC Jr, Shorr AF:Rational dosing of antimicrobial agents: pharmacokinetic and pharmacodynamic strategies. Am J Health Syst Pharm 66(Suppl 4):S23-S30,2009
12)Shiu J, Wang E, Tejani AM, et al:Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections. Cochrane Database Syst Rev CD008481,2013
13)Yost RJ, Cappelletty DM:The Retrospective Cohort ofExtended-Infusion Piperacillin-Tazobactam (RECEIPT) study: a multicenter study. Pharmacotherapy 31:767-775,2011
14)McNabb JJ, Nightingale CH, Quintiliani R, et al:Cost-effectiveness of ceftazidime by continuous infusion versus intermittent infusion for nosocomial pneumonia. Pharmacotherapy 21:549-555,2001
15)日本化学療法学会/日本TDM学会 抗菌薬TDMガイドライン作成委員会(編):抗菌薬TDMガイドライン2016,2016
16)Marquis KA, DeGrado JR, Labonville S, et al:Evaluation of a Pharmacist-Directed Vancomycin Dosing and Monitoring Pilot Program at a Tertiary Academic Medical Center. Ann Pharmacother 49:1009-1014,2015
17)Yu K, Rho J, Morcos M, et al:Evaluation of dedicated infectious diseases pharmacists on antimicrobial stewardship teams. Am J Health Syst Pharm 71:1019-1028,2014
18)Cappelletty D, Jacobs D:Evaluating the impact of a pharmacist's absence from an antimicrobial stewardship team. Am J Health Syst Pharm 70:1065-1069,2013
19)日本病院薬剤師会:感染制御認定薬剤師認定者,2016(http://www.jshp.or.jp/senmon/senmon2-7.pdf)
20)日本病院薬剤師会:感染制御専門薬剤師認定者,2016(http://www.jshp.or.jp/senmon/senmon2-8.pdf)
21)日本化学療法学会:抗菌化学療法認定薬剤師認定者一覧表(地域別),2016(http://www.chemotherapy.or.jp/qualification/list_pharmacist-area.pdf)
22)厚生労働省:平成27年(2015)医療施設(動態)調査・病院報告の概況,2015(http://www.mhlw.go.jp/toukei/saikin/hw/iryosd/15/dl/02_01.pdf)
23)National Matching Services Inc:ASHP Summary of Programs and Positions Offered and Filled for the 2016 Match Combined Phase I and Phase II,2016(https://www.natmatch.com/ashprmp/stats/2016summpos.html)
24)Carreno JJ, Kenney RM, Bloome M, et al:Evaluation of pharmacy generalists performing antimicrobial stewardship services. Am J Health Syst Pharm 72:1298-1303,2015
25)Bessesen MT, Ma A, Clegg D, et al:Antimicrobial Stewardship Programs: Comparison of a Program with Infectious Diseases Pharmacist Support to a Program with a Geographic Pharmacist Staffing Model. Hosp Pharm 50:477-483,2015
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