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文献概要

今月の特集1 知っておきたい感染症関連診療ガイドラインのエッセンス

性感染症 診断・治療ガイドライン—尿道炎を中心に

著者: 安田満1

所属機関: 1岐阜大学医学部附属病院泌尿器科

ページ範囲:P.44 - P.49

Point

●本ガイドラインでは17疾患を扱うが,頻度が高く薬剤耐性が問題となっている疾患は尿道炎である.

●尿道炎の診断では,まずは淋菌性尿道炎と非淋菌性尿道炎に大別する.

●淋菌の検出には鏡検法,培養法および核酸増幅法検査があるが,鏡検法は正確かつ最も迅速である.

●淋菌とマイコプラズマ・ジェニタリウムの薬剤耐性化が著しく,治療困難となりつつある.

参考文献

1)日本性感染症学会(編):性感染症 診断・治療 ガイドライン 2016.日性感染症会誌 27(Suppl):1-171,2016(http://jssti.umin.jp/guideline_c.html)(最終アクセス:2017年11月7日)
2)Ito S, Hanaoka N, Shimuta K, et al:Male non-gonococcal urethritis: From microbiological etiologies to demographic and clinical features. Int J Urol 23:325-331,2016
3)Seike K, Maeda S, Kubota Y, et al:Prevalence and morbidity of urethral Trichomonas vaginalis in Japanese men with or without urethritis. Sex Transm Infect 89:528-530,2013
4)Takahashi S, Kurimura Y, Hashimoto J, et al:Pharyngeal Neisseria gonorrhoeae detection in oral-throat wash specimens of male patients with urethritis. J Infect Chemother 14:442-444,2008
5)小島宗門,矢田康文,早瀬喜正:尿道炎の診断におけるメチレンブルー単染色を用いた尿道分泌物鏡検の有用性についての検討.日性感染症会誌 19:60,2008
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13)Takahashi S, Hamasuna R, Yasuda M, et al:Nationwide surveillance of the antimicrobial susceptibility of Chlamydia trachomatis from male urethritis in Japan. J Infect Chemother 22:581-586,2016
14)Yasuda M, Maeda S, Deguchi T:In vitro activity of fluoroquinolones against Mycoplasma genitalium and their bacteriological efficacy for treatment of M. genitalium-positive nongonococcal urethritis in men. Clin Infect Dis 41:1357-1359,2005
15)Shimada Y, Deguchi T, Nakane K, et al:Macrolide resistance-associated 23S rRNA mutation in Mycoplasma genitalium, Japan. Emerg Infect Dis 17:1148-1150,2011
16)Kikuchi M, Ito S, Yasuda M, et al:Remarkable increase in fluoroquinolone-resistant Mycoplasma genitalium in Japan. J Antimicrob Chemother 69:2376-2382,2014
17)Deguchi T, Ito S, Yasuda M, et al:Emergence of Mycoplasma genitalium with clinically significant fluoroquinolone resistance conferred by amino acid changes both in GyrA and ParC in Japan. J Infect Chemother 23:648-650,2017

掲載雑誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1367

印刷版ISSN:0485-1420

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