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雑誌文献

臨床検査62巻1号

2018年01月発行

文献概要

今月の特集2 心腎連関を理解する

心腎症候群とは

著者: 筒井裕之1

所属機関: 1九州大学大学院医学研究院循環器内科学

ページ範囲:P.52 - P.57

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●心不全では高頻度に慢性腎臓病(CKD)を合併する.

●心不全とCKDの合併は心腎症候群と呼ばれ,治療を困難にするだけでなく予後を悪化させる.

●心腎連関の病態形成には,心拍出量低下による腎灌流低下ばかりでなく心不全による腎うっ血も関与する.

●心腎症候群の有効な治療法は確立しておらず,研究のさらなる進展が望まれる.

参考文献

1)Ronco C, Haapio M, House AA, et al:Cardiorenal syndrome. J Am Coll Cardiol 52:1527-1539,2008
2)Ronco C, Ronco F:Cardio-renal syndromes: a systematic approach for consensus definition and classification. Heart Fail Rev 17:151-160,2012
3)Adams KF Jr, Fonarow GC, Emerman CL, et al:Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J 149:209-216,2005
4)Fonarow GC, Heywood JT:The confounding issue of comorbid renal insufficiency. Am J Med 119(Suppl1):S17-25,2006
5)Hamaguchi S, Tsuchihashi-Makaya M, Kinugawa S, et al:Chronic kidney disease as an independent risk for long-term adverse outcomes in patients hospitalized with heart failure in Japan. Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). Circ J 73:1442-1447,2009
6)Hillege HL, Girbes AR, de Kam PJ, et al:Renal function, neurohormonal activation, and survival in patients with chronic heart failure. Circulation 102:203-210,2000
7)Gottlieb SS, Abraham W, Butler J, et al:The prognostic importance of different definitions of worsening renal function in congestive heart failure. J Card Fail 8:136-141,2002
8)Smith GL, Vaccarino V, Kosiborod M, et al:Worsening renal function: what is a clinically meaningful change in creatinine during hospitalization with heart failure? J Card Fail 9:13-25,2003
9)Fonarow GC, Adams KF Jr, Abraham WT, et al:Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis. JAMA 293:572-580,2005
10)Tang WH, Mullens W:Cardiorenal syndrome in decompensated heart failure. Heart 96:255-260,2010
11)Palazzuoli A, Antonelli G, Nuti R:Anemia in Cardio-Renal Syndrome: clinical impact and pathophysiologic mechanisms. Heart Fail Rev 16:603-607,2011
12)Ronco C, McCullough P, Anker SD, et al:Cardio-renal syndromes: report from the consensus conference of the Acute Dialysis Quality Initiative. Eur Heart J 31:703-711,2010
13)Hillege HL, Nitsch D, Pfeffer MA, et al:Renal Function as a Predictor of Outcome in a Broad Spectrum of Patients With Heart Failure. Circulation 113:671-678,2006

掲載誌情報

出版社:株式会社医学書院

電子版ISSN:1882-1367

印刷版ISSN:0485-1420

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